Mostrar el registro sencillo del ítem

Impact of Intraventricular Septal Fiber Orientation on Cardiac Electromechanical Function.

dc.rights.licenseopenen_US
dc.contributor.authorRODRIGUEZ PADILLA, Jairo
dc.contributor.authorPETRAS, Argyrios
dc.contributor.authorMAGAT, Julie
hal.structure.identifierInstitut de Mathématiques de Bordeaux [IMB]
dc.contributor.authorBAYER, Jason
dc.contributor.authorBIHAN-POUDEC, Yann
dc.contributor.authorEL-HAMRANI, Dounia
hal.structure.identifierCentre de recherche Cardio-Thoracique de Bordeaux [Bordeaux] [CRCTB]
dc.contributor.authorRAMLUGUN, Girish
dc.contributor.authorNEIC, Aurel
dc.contributor.authorAUGUSTIN, Christoph
dc.contributor.authorVAILLANT, Fanny
dc.contributor.authorCONSTANTIN, Marion
hal.structure.identifierCentre de recherche Cardio-Thoracique de Bordeaux [Bordeaux] [CRCTB]
dc.contributor.authorBENOIST, David
dc.contributor.authorPOURTAU, Line
dc.contributor.authorDUBES, Virginie
dc.contributor.authorROGIER, Julien
hal.structure.identifierBiologie des maladies cardiovasculaires = Biology of Cardiovascular Diseases
dc.contributor.authorLABROUSSE, Louis
hal.structure.identifierCentre de recherche Cardio-Thoracique de Bordeaux [Bordeaux] [CRCTB]
dc.contributor.authorBERNUS, Olivier
IDREF: 185530761
dc.contributor.authorQUESSON, Bruno
dc.contributor.authorHAISSAGUERRE, Michel
dc.contributor.authorGSELL, Matthias
dc.contributor.authorPLANK, Gernot
hal.structure.identifierCentre de résonance magnétique des systèmes biologiques [CRMSB]
dc.contributor.authorOZENNE, Valéry
dc.contributor.authorVIGMOND, Edward
dc.date.accessioned2022-04-20T12:51:50Z
dc.date.available2022-04-20T12:51:50Z
dc.date.issued2022-03
dc.identifier.issn1522-1539en_US
dc.identifier.urihttps://oskar-bordeaux.fr/handle/20.500.12278/139877
dc.description.abstractEnCardiac fiber direction is an important factor determining the propagation of electrical activity, as well as the development of mechanical force. In this paper, we imaged the ventricles of several species with special attention to the intraventricular septum to determine the functional consequences of septal fiber organization. First, we identify a dual-layer organization of the fiber orientation in the intraventricular septum of ex-vivo sheep hearts using diffusion tensor imaging at high field MRI. To expand the scope of the results, we investigate the presence of similar fiber organization on five mammalian species (rat, canine, pig, sheep, human) and highlight the continuity of the layer with the moderator band in large mammalian species. We implemented the measured septal fiber fields in 3D electromechanical computer models to assess the impact of the fiber orientation. The downward fibers produced a diamond activation pattern superficially in the RV. Electromechanically, there was very little change in pressure volume loops although the stress distribution was altered. In conclusion, we clarified that the RV septum has a downwardly directed superficial layer in larger mammalian species, which can have modest effects on stress distribution.
dc.language.isoENen_US
dc.subject.enIntraventricular Septum
dc.subject.enFiber Orientation
dc.subject.enElectromechanical models
dc.subject.enDiffusion Tensor imaging
dc.subject.enNormal structural discontinuities
dc.title.enImpact of Intraventricular Septal Fiber Orientation on Cardiac Electromechanical Function.
dc.title.alternativeAm J Physiol Heart Circ Physiolen_US
dc.typeArticle de revueen_US
dc.identifier.doi10.1152/ajpheart.00050.2022en_US
dc.subject.halSciences du Vivant [q-bio]/Ingénierie biomédicaleen_US
dc.identifier.pubmed35302879en_US
bordeaux.journalAJP - Heart and Circulatory Physiologyen_US
bordeaux.hal.laboratoriesCentre de Résonance Magnétique des Systèmes Biologiques (CRMSB) - UMR 5536en_US
bordeaux.institutionUniversité de Bordeauxen_US
bordeaux.institutionCNRSen_US
bordeaux.institutionINSERM
bordeaux.peerReviewedouien_US
bordeaux.inpressnonen_US
bordeaux.import.sourcepubmed
hal.identifierhal-03647387
hal.version1
hal.date.transferred2022-04-20T12:51:53Z
hal.exporttrue
workflow.import.sourcepubmed
dc.rights.ccPas de Licence CCen_US
bordeaux.COinSctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=AJP%20-%20Heart%20and%20Circulatory%20Physiology&rft.date=2022-03&rft.eissn=1522-1539&rft.issn=1522-1539&rft.au=RODRIGUEZ%20PADILLA,%20Jairo&PETRAS,%20Argyrios&MAGAT,%20Julie&BAYER,%20Jason&BIHAN-POUDEC,%20Yann&rft.genre=article


Archivos en el ítem

ArchivosTamañoFormatoVer

No hay archivos asociados a este ítem.

Este ítem aparece en la(s) siguiente(s) colección(ones)

Mostrar el registro sencillo del ítem