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Models of biological effects of radiation in the Geant4 Toolkit

dc.contributor.authorCHAUVIE, S.
hal.structure.identifierLaboratoire de Physique Corpusculaire - Clermont-Ferrand [LPC]
dc.contributor.authorFRANCIS, Z.
dc.contributor.authorGUATELLI, S.
hal.structure.identifierCentre d'Etudes Nucléaires de Bordeaux Gradignan [CENBG]
dc.contributor.authorINCERTI, S.
dc.contributor.authorMASCIALINO, B.
hal.structure.identifierLaboratoire de Physique Corpusculaire - Clermont-Ferrand [LPC]
dc.contributor.authorMONTAROU, Gerard
hal.structure.identifierCentre d'Etudes Nucléaires de Bordeaux Gradignan [CENBG]
dc.contributor.authorMORETTO, P.
dc.contributor.authorNIEMINEN, P.
dc.contributor.authorPIA, M.G.
dc.date.issued2006
dc.date.conference2006-10-29
dc.description.abstractEnA project, named Geant4-DNA, is in progress to extend the Geant4 simulation toolkit to model the effects of radiation with biological systems at cellular and DNA level. The first component implemented in the first development cycle of the project describes the fractional survival of a population of cells irradiated with photons or charged particles. The software system developed provides the user the option to choose among a small set of alternative models for the calculation of mammalian cell survival after irradiation. The flexible design adopted makes the system open to further extension to implement other cell survival models available in literature. The preliminary design of a prototype of the cell survival models implemented and preliminary results in some selected cell lines are described.
dc.language.isoen
dc.source.titleProceedings of nuclear science symposium 2006
dc.title.enModels of biological effects of radiation in the Geant4 Toolkit
dc.typeCommunication dans un congrès
dc.subject.halPhysique [physics]/Physique [physics]/Biophysique [physics.bio-ph]
dc.subject.halPhysique [physics]/Physique [physics]/Instrumentations et Détecteurs [physics.ins-det]
bordeaux.countryUS
bordeaux.title.proceedingProceedings of nuclear science symposium 2006
bordeaux.conference.citySan Diego
bordeaux.peerReviewedoui
hal.identifierin2p3-00134456
hal.version1
hal.invitednon
hal.proceedingsoui
hal.conference.end2006-11-04
hal.popularnon
hal.audienceInternationale
dc.subject.itMonteCarlo
dc.subject.itGeant4
dc.subject.itRadiobiological damage
dc.subject.itRadiobiological modeling
dc.subject.itCell survival
hal.origin.linkhttps://hal.archives-ouvertes.fr//in2p3-00134456v1
bordeaux.COinSctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.btitle=Proceedings%20of%20nuclear%20science%20symposium%202006&rft.date=2006&rft.au=CHAUVIE,%20S.&FRANCIS,%20Z.&GUATELLI,%20S.&INCERTI,%20S.&MASCIALINO,%20B.&rft.genre=unknown


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