Micro-PIXE characterization of interactions between a sol-gel derived bioactive glass and biological fluids
| hal.structure.identifier | Laboratoire de Physique Corpusculaire - Clermont-Ferrand [LPC] | |
| dc.contributor.author | LAO, Jonathan | |
| hal.structure.identifier | Laboratoire des Matériaux Inorganiques [LMI] | |
| dc.contributor.author | NEDELEC, Jean-Marie | |
| hal.structure.identifier | Centre d'Etudes Nucléaires de Bordeaux Gradignan [CENBG] | |
| dc.contributor.author | MORETTO, Philippe | |
| hal.structure.identifier | Laboratoire de Physique Corpusculaire - Clermont-Ferrand [LPC] | |
| dc.contributor.author | JALLOT, Edouard | |
| dc.date.issued | 2006-02-28 | |
| dc.identifier.issn | 0168-583X | |
| dc.description.abstractEn | Bioactive glasses possess the ability to bond to living tissues through the formation of a calcium phosphate-rich layer at their interface with living tissues. This paper reports the different steps of this bioactivity process via a complete micro-PIXE characterization of a sol-gel derived SiO2-CaO bioactive glass in contact with biological fluids for different delays. Multi-elemental cartography at the glass/biological fluids interface together with major and trace elements quantification permit a better understanding of the five reaction stages involved in the bioactivity mechanisms. The presence of phosphorus was detected at the periphery of the material within 6 h of interaction with biological fluids. A calcium phosphate-rich layer containing magnesium is formed after a few days of interaction and presence of bone-like apatite is deduced from the calculation of the Ca/P ratio at the material interface. That is of deep interest for clinical applications, because this biologically active behavior results in the formation of a strong interfacial bond between the glass and host tissues, and will stimulate bone-cell proliferation. | |
| dc.language.iso | en | |
| dc.publisher | Elsevier | |
| dc.subject.en | sol-gel | |
| dc.subject.en | PIXE-RBS methods | |
| dc.subject.en | biomaterials | |
| dc.subject.en | bioactive glass | |
| dc.subject.en | sol-gel. | |
| dc.title.en | Micro-PIXE characterization of interactions between a sol-gel derived bioactive glass and biological fluids | |
| dc.type | Article de revue | |
| dc.identifier.doi | 10.1016/j.nimb.2005.12.049 | |
| dc.subject.hal | Chimie/Matériaux | |
| bordeaux.journal | Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms | |
| bordeaux.page | 511-518 | |
| bordeaux.volume | 245 | |
| bordeaux.peerReviewed | oui | |
| hal.identifier | hal-00154776 | |
| hal.version | 1 | |
| hal.popular | non | |
| hal.audience | Non spécifiée | |
| hal.origin.link | https://hal.archives-ouvertes.fr//hal-00154776v1 | |
| bordeaux.COinS | ctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=Nuclear%20Instruments%20and%20Methods%20in%20Physics%20Research%20Section%20B:%20Beam%20Interactions%20with%20Materials%20and%20Atoms&rft.date=2006-02-28&rft.volume=245&rft.spage=511-518&rft.epage=511-518&rft.eissn=0168-583X&rft.issn=0168-583X&rft.au=LAO,%20Jonathan&NEDELEC,%20Jean-Marie&MORETTO,%20Philippe&JALLOT,%20Edouard&rft.genre=article |
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