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Is there penetration of titania nanoparticles in sunscreens through skin? A comparative electron and ion microscopy study
dc.contributor.author | GONTIER, E. | |
dc.contributor.author | YNSA, M. | |
dc.contributor.author | BIACUTEROACUTE, T. | |
dc.contributor.author | HUNYADI, J. | |
dc.contributor.author | KISS, B. | |
dc.contributor.author | GAACUTESPAACUTER, K. | |
dc.contributor.author | PINHEIRO, T. | |
dc.contributor.author | SILVA, J. | |
dc.contributor.author | FILIPE, P. | |
dc.contributor.author | STACHURA, J. | |
dc.contributor.author | DABROS, W. | |
dc.contributor.author | REINERT, T. | |
hal.structure.identifier | Centre d'Etudes Nucléaires de Bordeaux Gradignan [CENBG] | |
dc.contributor.author | MORETTO, P. | |
dc.contributor.author | BUTZ, T. | |
dc.contributor.author | SURLEGRAVEVE-BAZEILLE, J. | |
dc.date.issued | 2008-12-04 | |
dc.identifier.issn | 1743-5390 | |
dc.description.abstractEn | We report on a comparative study by Transmission Electron Microscopy (HRTEM) and Scanning Transmission Ion Microscopy (STIM) combined with Rutherford Backscattering Spectrometry (RBS) and Particle Induced X-Ray Emission (PIXE) on ultra-thin and thin cross-sections, respectively, of various skin samples (porcine skin, healthy human skin, human skin grafted on a severe combined immuno-deficient mouse model) to which we applied topically various formulations containing titanium dioxide (TiO2) nanoparticles with primary particle sizes in the range from 20-100 nm. Whereas the HRTEM and STIM/PIXE images reveal clear differences - mainly related to the different thickness of the cross-sections - they unambiguously show that penetration of TiO2 nanoparticles is restricted to the topmost 3-5 corneocyte layers of the stratum corneum (SC). | |
dc.language.iso | en | |
dc.publisher | Taylor & Francis | |
dc.title.en | Is there penetration of titania nanoparticles in sunscreens through skin? A comparative electron and ion microscopy study | |
dc.type | Article de revue | |
dc.identifier.doi | 10.1080/17435390802538508 | |
dc.subject.hal | Sciences du Vivant [q-bio]/Toxicologie | |
dc.subject.hal | Physique [physics]/Physique [physics]/Biophysique [physics.bio-ph] | |
dc.subject.hal | Sciences du Vivant [q-bio]/Ecologie, Environnement | |
bordeaux.journal | Nanotoxicology | |
bordeaux.page | 218-231 | |
bordeaux.volume | 2 | |
bordeaux.peerReviewed | oui | |
hal.identifier | in2p3-00355163 | |
hal.version | 1 | |
hal.popular | non | |
hal.audience | Non spécifiée | |
hal.origin.link | https://hal.archives-ouvertes.fr//in2p3-00355163v1 | |
bordeaux.COinS | ctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=Nanotoxicology&rft.date=2008-12-04&rft.volume=2&rft.spage=218-231&rft.epage=218-231&rft.eissn=1743-5390&rft.issn=1743-5390&rft.au=GONTIER,%20E.&YNSA,%20M.&BIACUTEROACUTE,%20T.&HUNYADI,%20J.&KISS,%20B.&rft.genre=article |
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