How I manage pregnancy in women with Glanzmann thrombasthenia.
| dc.rights.license | open | en_US |
| hal.structure.identifier | Biologie des maladies cardiovasculaires = Biology of Cardiovascular Diseases | |
| dc.contributor.author | FIORE, Mathieu | |
| hal.structure.identifier | CHU Bordeaux | |
| dc.contributor.author | SENTILHES, Loïc | |
| hal.structure.identifier | Hôpital Bicêtre [AP-HP, Le Kremlin-Bicêtre] | |
| dc.contributor.author | D'OIRON, Roseline | |
| dc.date.accessioned | 2022-04-07T12:17:31Z | |
| dc.date.available | 2022-04-07T12:17:31Z | |
| dc.date.issued | 2022-03-14 | |
| dc.identifier.issn | 1528-0020 | en_US |
| dc.identifier.uri | https://oskar-bordeaux.fr/handle/20.500.12278/136609 | |
| dc.description.abstractEn | Glanzmann thrombasthenia (GT) is a rare inherited platelet function disorder caused by a quantitative and/or qualitative defect of the αIIbβ3 integrin. Pregnancy and delivery is a recognized risk period for bleeding in women with GT. The newborn may also be affected by fetal and neonatal immune thrombocytopenia induced by the transplacental passage of maternal anti-αIIbβ3 antibodies, which can lead to severe hemorrhage and fetal loss. Pregnancy in GT women thus requires a multidisciplinary approach, including prepregnancy counseling, and a treatment plan for delivery for both the mother and child. In this article, we summarize the current knowledge on pregnancy in women with GT and describe how we manage this severe platelet disorder in our clinical practice. | |
| dc.language.iso | EN | en_US |
| dc.subject | ARTICLE CLINIQUE | |
| dc.subject.en | Platelets and Thrombopoiesis | |
| dc.title.en | How I manage pregnancy in women with Glanzmann thrombasthenia. | |
| dc.title.alternative | Blood | en_US |
| dc.type | Article de revue | en_US |
| dc.identifier.doi | 10.1182/blood.2021011595 | en_US |
| dc.subject.hal | Sciences du Vivant [q-bio]/Médecine humaine et pathologie | en_US |
| dc.identifier.pubmed | 35286390 | en_US |
| bordeaux.journal | Blood | en_US |
| bordeaux.hal.laboratories | Biologie des maladies cardiovasculaires (BMC) - UMR 1034 | en_US |
| bordeaux.institution | Université de Bordeaux | en_US |
| bordeaux.institution | INSERM | en_US |
| bordeaux.peerReviewed | oui | en_US |
| bordeaux.inpress | non | en_US |
| bordeaux.import.source | pubmed | |
| hal.identifier | hal-03634120 | |
| hal.version | 1 | |
| hal.date.transferred | 2022-04-07T12:17:33Z | |
| hal.export | true | |
| workflow.import.source | pubmed | |
| dc.rights.cc | Pas de Licence CC | en_US |
| bordeaux.COinS | ctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=Blood&rft.date=2022-03-14&rft.eissn=1528-0020&rft.issn=1528-0020&rft.au=FIORE,%20Mathieu&SENTILHES,%20Lo%C3%AFc&D'OIRON,%20Roseline&rft.genre=article |
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