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dc.rights.licenseopenen_US
dc.contributor.authorBECQUET, Valentine
dc.contributor.authorNOUAMAN, Marcellin
hal.structure.identifierBordeaux population health [BPH]
dc.contributor.authorPLAZY, Melanie
dc.contributor.authorAGOUA, Aline
dc.contributor.authorZEBAGO, Clemence
dc.contributor.authorDAO, Herve
dc.contributor.authorMONTOYO, Alice
dc.contributor.authorJARY, Aude
dc.contributor.authorCOFFIE, Patrick A.
dc.contributor.authorEHOLIE, Serge
dc.contributor.authorLARMARANGE, Joseph
dc.contributor.authorAND THE, Anrs Princesse Team
dc.date.accessioned2022-01-18T13:04:11Z
dc.date.available2022-01-18T13:04:11Z
dc.date.issued2021-12-04
dc.identifier.issn1471-2458 (Electronic) 1471-2458 (Linking)en_US
dc.identifier.urihttps://oskar-bordeaux.fr/handle/20.500.12278/124420
dc.description.abstractEnBACKGROUND: Pre-exposure prophylaxis (PrEP) is recommended by the WHO for HIV prevention among female sex workers (FSWs). A study conducted in 2016-2017 in Côte d'Ivoire showed that if PrEP is acceptable, FSWs also have many uncovered sexual health needs. Based on this evidence, the ANRS 12381 PRINCESSE project was developed in collaboration with a community-based organization. The main objective is to develop, document, and analyze a comprehensive sexual and reproductive healthcare package among FSWs in Côte d'Ivoire. METHODS: PRINCESSE is an open, single-arm interventional cohort of 500 FSWs in San Pedro (Côte d'Ivoire) and its surroundings. Recruitment started on November 26th, 2019 and is ongoing; the cohort is planned to last at least 30 months. The healthcare package (including HIV, hepatitis B, and sexually transmitted infection management, pregnancy screening, and contraception) is available both at mobile clinics organized for a quarterly follow-up (10 intervention sites, each site being visited every two weeks) and at a fixed clinic. Four waves of data collection were implemented: (i) clinical and safety data; (ii) socio-behavioral questionnaires; (iii) biological data; and (iv) in-depth interviews with female participants. Four additional waves of data collection are scheduled outside the cohort itself: (i) the medical and activity records of Aprosam for the PRINCESSE participants; (ii) the medical records of HIV+ FSW patients not participating in the PRINCESSE cohort, and routinely examined by Aprosam; (iii) in-depth interviews with key informants in the FSW community; and (iv) in-depth interviews with PRINCESSE follow-up actors. DISCUSSION: The PRINCESSE project is one of the first interventions offering HIV oral PrEP as part of a more global sexual healthcare package targeting both HIV- and HIV+ women. Second, STIs and viral hepatitis B care were offered to all participants, regardless of their willingness to use PrEP. Another innovation is the implementation of mobile clinics for chronic/quarterly care. In terms of research, PRINCESSE is a comprehensive, interdisciplinary project combining clinical, biological, epidemiological, and social specific objectives and outcomes to document the operational challenges of a multidisease program in real-life conditions. TRIAL REGISTRATION: The PRINCESSE project was registered on the Clinicaltrial.gov website ( NCT03985085 ) on June 13, 2019.
dc.language.isoENen_US
dc.rightsAttribution 3.0 United States*
dc.rights.urihttp://creativecommons.org/licenses/by/3.0/us/*
dc.subject.enHIV prevention
dc.subject.enSexual and reproductive health
dc.subject.enSexually transmitted infections (STIs) hepatitis B
dc.subject.enPre-exposure prophylaxis (PrEP)
dc.subject.enSex work
dc.subject.enMixed-methods research
dc.subject.enMobile clinics
dc.subject.enCôte d’Ivoire
dc.title.enA community-based healthcare package combining testing and prevention tools, including pre-exposure prophylaxis (PrEP), immediate HIV treatment, management of hepatitis B virus, and sexual and reproductive health (SRH), targeting female sex workers (FSWs) in Cote d'Ivoire: the ANRS 12381 PRINCESSE project
dc.typeArticle de revueen_US
dc.identifier.doi10.1186/s12889-021-12235-0en_US
dc.subject.halSciences du Vivant [q-bio]/Santé publique et épidémiologieen_US
dc.identifier.pubmed34863122en_US
bordeaux.journalBMC Public Healthen_US
bordeaux.page2214en_US
bordeaux.volume21en_US
bordeaux.hal.laboratoriesBordeaux Population Health Research Center (BPH) - UMR 1219en_US
bordeaux.issue1en_US
bordeaux.institutionUniversité de Bordeauxen_US
bordeaux.institutionINSERMen_US
bordeaux.teamIDLICen_US
bordeaux.teamPACCIen_US
bordeaux.peerReviewedouien_US
bordeaux.inpressnonen_US
bordeaux.identifier.funderIDInstitut National de la Santé et de la Recherche Médicaleen_US
bordeaux.identifier.funderIDAgence Nationale de Recherches sur le Sida et les Hépatites Viralesen_US
hal.exportfalse
dc.rights.ccPas de Licence CCen_US
bordeaux.COinSctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=BMC%20Public%20Health&rft.date=2021-12-04&rft.volume=21&rft.issue=1&rft.spage=2214&rft.epage=2214&rft.eissn=1471-2458%20(Electronic)%201471-2458%20(Linking)&rft.issn=1471-2458%20(Electronic)%201471-2458%20(Linking)&rft.au=BECQUET,%20Valentine&NOUAMAN,%20Marcellin&PLAZY,%20Melanie&AGOUA,%20Aline&ZEBAGO,%20Clemence&rft.genre=article


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