High-resolution Free-breathing late gadolinium enhancement Cardiovascular magnetic resonance to diagnose myocardial injuries following COVID-19 infection
| dc.rights.license | open | en_US |
| dc.contributor.author | BUSTIN, Aurelien | |
| dc.contributor.author | SRIDI, Soumaya | |
| dc.contributor.author | GRAVINAY, Pierre | |
| dc.contributor.author | LEGGHE, Benoit | |
| dc.contributor.author | GOSSE, Philippe | |
| dc.contributor.author | OUATTARA, Alexandre | |
| dc.contributor.author | ROZE, Hadrien | |
| dc.contributor.author | COSTE, Pierre | |
| dc.contributor.author | GERBAUD, Edouard | |
| dc.contributor.author | DESCLAUX, Arnaud | |
| dc.contributor.author | BOYER, Alexandre | |
| dc.contributor.author | PREVEL, Renaud | |
| dc.contributor.author | GRUSON, Didier | |
| hal.structure.identifier | Bordeaux population health [BPH] | |
| dc.contributor.author | BONNET, Fabrice | |
| dc.contributor.author | ISSA, Nahema | |
| hal.structure.identifier | Centre de recherche Cardio-Thoracique de Bordeaux [Bordeaux] [CRCTB] | |
| dc.contributor.author | MONTAUDON, Michel | |
| hal.structure.identifier | Centre de recherche Cardio-Thoracique de Bordeaux [Bordeaux] [CRCTB] | |
| dc.contributor.author | LAURENT, Francois | |
| dc.contributor.author | STUBER, Matthias | |
| dc.contributor.author | CAMOU, Fabrice | |
| dc.contributor.author | COCHET, Hubert | |
| dc.date.accessioned | 2021-11-22T12:58:40Z | |
| dc.date.available | 2021-11-22T12:58:40Z | |
| dc.date.issued | 2021-09-20 | |
| dc.identifier.issn | 0720-048X (Print) 0720-048x | en_US |
| dc.identifier.uri | https://oskar-bordeaux.fr/handle/20.500.12278/123912 | |
| dc.description.abstractEn | PURPOSE: High-resolution free-breathing late gadolinium enhancement (HR-LGE) was shown valuable for the diagnosis of acute coronary syndromes with non-obstructed coronary arteries. The method may be useful to detect COVID-related myocardial injuries but is hampered by prolonged acquisition times. We aimed to introduce an accelerated HR-LGE technique for the diagnosis of COVID-related myocardial injuries. METHOD: An undersampled navigator-gated HR-LGE (acquired resolution of 1.25 mm(3)) sequence combined with advanced patch-based low-rank reconstruction was developed and validated in a phantom and in 23 patients with structural heart disease (test cohort; 15 men; 55 ± 16 years). Twenty patients with laboratory-confirmed COVID-19 infection associated with troponin rise (COVID cohort; 15 men; 46 ± 24 years) prospectively underwent cardiovascular magnetic resonance (CMR) with the proposed sequence in our center. Image sharpness, quality, signal intensity differences and diagnostic value of free-breathing HR-LGE were compared against conventional breath-held low-resolution LGE (LR-LGE, voxel size 1.8x1.4x6mm). RESULTS: Structures sharpness in the phantom showed no differences with the fully sampled image up to an undersampling factor of x3.8 (P > 0.5). In patients (N = 43), this acceleration allowed for acquisition times of 7min21s ± 1min12s at 1.25 mm(3) resolution. Compared with LR-LGE, HR-LGE showed higher image quality (P = 0.03) and comparable signal intensity differences (P > 0.5). In patients with structural heart disease, all LGE-positive segments on LR-LGE were also detected on HR-LGE (80/391) with 21 additional enhanced segments visible only on HR-LGE (101/391, P < 0.001). In 4 patients with COVID-19 history, HR-LGE was definitely positive while LR-LGE was either definitely negative (1 microinfarction and 1 myocarditis) or inconclusive (2 myocarditis). CONCLUSIONS: Undersampled free-breathing isotropic HR-LGE can detect additional areas of late enhancement as compared to conventional breath-held LR-LGE. In patients with history of COVID-19 infection associated with troponin rise, the method allows for detailed characterization of myocardial injuries in acceptable scan times and without the need for repeated breath holds. | |
| dc.description.sponsorship | Plateforme multi-modale d'exploration en cardiologie | en_US |
| dc.language.iso | EN | en_US |
| dc.rights | Attribution-NonCommercial-NoDerivs 3.0 United States | * |
| dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/3.0/us/ | * |
| dc.subject.en | Cardiac Magnetic Resonance Imaging | |
| dc.subject.en | High-resolution | |
| dc.subject.en | Late Gadolinium Enhancement | |
| dc.subject.en | COVID-19 | |
| dc.title.en | High-resolution Free-breathing late gadolinium enhancement Cardiovascular magnetic resonance to diagnose myocardial injuries following COVID-19 infection | |
| dc.type | Article de revue | en_US |
| dc.identifier.doi | 10.1016/j.ejrad.2021.109960 | en_US |
| dc.subject.hal | Sciences du Vivant [q-bio]/Santé publique et épidémiologie | en_US |
| dc.identifier.pubmed | 34600236 | en_US |
| bordeaux.journal | European Journal of Radiology | en_US |
| bordeaux.page | 109960 | en_US |
| bordeaux.volume | 144 | en_US |
| bordeaux.hal.laboratories | Bordeaux Population Health Research Center (BPH) - UMR 1219 | en_US |
| bordeaux.institution | Université de Bordeaux | en_US |
| bordeaux.institution | INSERM | en_US |
| bordeaux.team | MORPH3Eus | en_US |
| bordeaux.peerReviewed | oui | en_US |
| bordeaux.inpress | non | en_US |
| bordeaux.identifier.funderID | Agence Nationale de la Recherche | en_US |
| hal.identifier | hal-03440211 | |
| hal.version | 1 | |
| hal.date.transferred | 2021-11-22T12:58:47Z | |
| hal.export | true | |
| dc.rights.cc | Pas de Licence CC | en_US |
| bordeaux.COinS | ctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=European%20Journal%20of%20Radiology&rft.date=2021-09-20&rft.volume=144&rft.spage=109960&rft.epage=109960&rft.eissn=0720-048X%20(Print)%200720-048x&rft.issn=0720-048X%20(Print)%200720-048x&rft.au=BUSTIN,%20Aurelien&SRIDI,%20Soumaya&GRAVINAY,%20Pierre&LEGGHE,%20Benoit&GOSSE,%20Philippe&rft.genre=article |
