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Management of bleeding and invasive procedures in haemophilia A patients with inhibitor treated with emicizumab (Hemlibra®): Proposals from the French network on inherited bleeding disorders (MHEMO), the French Reference Centre on Haemophilia, in collaboration with the French Working Group on Perioperative Haemostasis (GIHP)

dc.rights.licenseauthentificationen_US
dc.contributor.authorSUSEN, Sophie
dc.contributor.authorGRUEL, Yves
dc.contributor.authorGODIER, Anne
dc.contributor.authorHARROCHE, Annie
dc.contributor.authorCHAMBOST, Herve
dc.contributor.authorLASNE, Dominique
dc.contributor.authorRAUCH, Antoine
hal.structure.identifierBiologie des maladies cardiovasculaires = Biology of Cardiovascular Diseases
dc.contributor.authorROULLET, Stéphanie
dc.contributor.authorFONTANA, Pierre
dc.contributor.authorGOUDEMAND, Jenny
dc.contributor.authorDE MAISTRE, Emmanuel
dc.contributor.authorCHAMOUARD, Valerie
dc.contributor.authorWIBAUT, Bénédicte
dc.contributor.authorALBALADEJO, Pierre
dc.contributor.authorNÉGRIER, Claude
dc.date.accessioned2020-11-10T11:53:01Z
dc.date.available2020-11-10T11:53:01Z
dc.date.issued2019-09
dc.identifier.issn1351-8216, 1365-2516en_US
dc.identifier.urihttps://oskar-bordeaux.fr/handle/20.500.12278/12203
dc.description.abstractEnINTRODUCTION: Emicizumab (Hemlibra® ) recently became available and requires an adaptation for managing bleeding, suspected bleeding and emergency or scheduled invasive procedures in haemophilia A patients with inhibitor. This implicates a multidisciplinary approach and redaction of recommendations for care that must be regularly adapted to the available data. AIM: The following text aims to provide a guide for the management of people with haemophilia A with inhibitor treated with emicizumab in case of bleeding or invasives procedures. METHODS: The French network on inherited bleeding disorders (MHEMO), the French Reference Centre on Haemophilia (CRH), in collaboration with the French Working Group on Perioperative Haemostasis (GIHP) have been working together to make proposals for the management of these situations. RESULTS: Haemostatic treatment and other medications should be given stepwise, according to the severity and location of the bleeding or the risk of bleeding of the procedure as well as the haemostatic response obtained at each step in order to ensure an optimal benefit/risk ratio. CONCLUSION: The lack of data means that it is only possible to issue proposals rather than recommendations.
dc.language.isoENen_US
dc.subjectArticle CLINIQUE
dc.title.enManagement of bleeding and invasive procedures in haemophilia A patients with inhibitor treated with emicizumab (Hemlibra®): Proposals from the French network on inherited bleeding disorders (MHEMO), the French Reference Centre on Haemophilia, in collaboration with the French Working Group on Perioperative Haemostasis (GIHP)
dc.typeArticle de revueen_US
dc.identifier.doi10.1111/hae.13817en_US
dc.subject.halSciences du Vivant [q-bio]/Médecine humaine et pathologieen_US
bordeaux.journalHaemophiliaen_US
bordeaux.page731–737en_US
bordeaux.volume25en_US
bordeaux.hal.laboratoriesBiologie des maladies cardiovasculaires - U1034en_US
bordeaux.issue5en_US
bordeaux.institutionUniversité de Bordeauxen_US
bordeaux.peerReviewedouien_US
bordeaux.inpressnonen_US
hal.exportfalse
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