Dense B-Scan Optical Coherence Tomography Angiography
| dc.rights.license | open | en_US |
| dc.contributor.author | FREUND, K. B. | |
| hal.structure.identifier | Bordeaux population health [BPH] | |
| dc.contributor.author | GATTOUSSI, Sarra
ORCID: 0000-0002-8905-7112 | |
| dc.contributor.author | LEONG, B. C. S. | |
| dc.date.accessioned | 2020-11-10T10:17:01Z | |
| dc.date.available | 2020-11-10T10:17:01Z | |
| dc.date.issued | 2018-06 | |
| dc.identifier.issn | 0002-9394 | en_US |
| dc.identifier.uri | https://oskar-bordeaux.fr/handle/20.500.12278/12184 | |
| dc.description.abstractEn | PURPOSE: To describe a novel imaging technique, which we call "dense B-scan optical coherence tomography angiography" (DB OCTA), in which thin dense raster scans are used to produce highly resolved structural B-scans with superimposed flow signal that provide precise correlation between retinal microstructure and blood flow. DESIGN: Observational case series. METHODS: Normal eyes and eyes with macular findings of interest were imaged with DB OCTA in which 150-400 OCT B-scans were acquired within a narrow area (from a single line to 1 degree) with a width of 10-30 degrees. B-scans containing 5-7 consecutive frames were processed for OCTA signal and then combined and visualized post-acquisition by application of a Gaussian filter across neighboring scans. The result was a single, smoothed, high-resolution image that contained both structural and flow information. Tracked follow-up DB OCTA was used to detect subtle changes in pathology over time. RESULTS: Two hundred and thirty-seven eyes from 205 subjects aged 18-100 years (mean 72.88 +/- 14.74 years) with a diverse range of macular findings were imaged with DB OCTA. Highly resolved scans showing precise localization of flow signal were readily obtained, even in patients with poor visual acuity and/or poor fixation. We present clinical examples that demonstrate the utility of DB OCTA for visualizing the associations between retinal microstructure and blood flow. CONCLUSIONS: DB OCTA enables precise correlation between retinal microstructure and blood flow. The ability to obtain accurately aligned follow-up DB OCTA studies has the potential to refine the understanding and clinical management of a wide range of macular diseases. | |
| dc.language.iso | EN | en_US |
| dc.subject.en | LEHA | |
| dc.title.en | Dense B-Scan Optical Coherence Tomography Angiography | |
| dc.title.alternative | Am J Ophthalmol | en_US |
| dc.type | Article de revue | en_US |
| dc.identifier.doi | 10.1016/j.ajo.2018.03.029 | en_US |
| dc.subject.hal | Sciences du Vivant [q-bio]/Santé publique et épidémiologie | en_US |
| dc.identifier.pubmed | 29601820 | en_US |
| bordeaux.journal | American journal of ophthalmology | en_US |
| bordeaux.page | 78-88 | en_US |
| bordeaux.volume | 190 | en_US |
| bordeaux.hal.laboratories | Bordeaux Population Health Research Center (BPH) - U1219 | en_US |
| bordeaux.institution | Université de Bordeaux | en_US |
| bordeaux.team | LEHA_BPH | |
| bordeaux.team | LEHA_BPH | |
| bordeaux.peerReviewed | oui | en_US |
| bordeaux.inpress | non | en_US |
| hal.identifier | hal-02997749 | |
| hal.version | 1 | |
| hal.date.transferred | 2020-11-10T10:17:04Z | |
| hal.export | true | |
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