Afficher la notice abrégée

The MRi-Share database: brain imaging in a cross-sectional cohort of 1870 university students

dc.rights.licenseopenen_US
atmire.cua.enabledHEALTHY_BPH
hal.structure.identifierInstitut des Maladies Neurodégénératives [Bordeaux] [IMN]
dc.contributor.authorTSUCHIDA, Ami
hal.structure.identifierInstitut des Maladies Neurodégénératives [Bordeaux] [IMN]
dc.contributor.authorLAURENT, Alexandre
hal.structure.identifierInstitut des Maladies Neurodégénératives [Bordeaux] [IMN]
dc.contributor.authorCRIVELLO, Fabrice
hal.structure.identifierInstitut des Maladies Neurodégénératives [Bordeaux] [IMN]
dc.contributor.authorPETIT, Laurent
hal.structure.identifierInstitut des Maladies Neurodégénératives [Bordeaux] [IMN]
dc.contributor.authorJOLIOT, Marc
hal.structure.identifierInstitut des Maladies Neurodégénératives [Bordeaux] [IMN]
dc.contributor.authorPEPE, Antonietta
hal.structure.identifierInstitut des Maladies Neurodégénératives [Bordeaux] [IMN]
dc.contributor.authorBEGUEDOU, Naka
hal.structure.identifierInstitut des Maladies Neurodégénératives [Bordeaux] [IMN]
dc.contributor.authorGUEYE, Marie-Fateye
hal.structure.identifierInstitut des Maladies Neurodégénératives [Bordeaux] [IMN]
dc.contributor.authorVERRECCHIA, Violaine
hal.structure.identifierInstitut des Maladies Neurodégénératives [Bordeaux] [IMN]
dc.contributor.authorNOZAIS, Victor
hal.structure.identifierInstitut des Maladies Neurodégénératives [Bordeaux] [IMN]
dc.contributor.authorZAGO, Laure
hal.structure.identifierInstitut des Maladies Neurodégénératives [Bordeaux] [IMN]
dc.contributor.authorMELLET, Emmanuel
hal.structure.identifierBordeaux population health [BPH]
dc.contributor.authorDEBETTE, Stephanie
hal.structure.identifierBordeaux population health [BPH]
dc.contributor.authorTZOURIO, Christophe
hal.structure.identifierInstitut des Maladies Neurodégénératives [Bordeaux] [IMN]
dc.contributor.authorMAZOYER, Bernard
dc.date.accessioned2021-08-30T10:05:51Z
dc.date.available2021-08-30T10:05:51Z
dc.date.issued2021-07-20
dc.identifier.issn1863-2653en_US
dc.identifier.urihttps://oskar-bordeaux.fr/handle/20.500.12278/110251
dc.description.abstractEnWe report on MRi-Share, a multi-modal brain MRI database acquired in a unique sample of 1870 young healthy adults, aged 18-35 years, while undergoing university-level education. MRi-Share contains structural (T1 and FLAIR), diffusion (multispectral), susceptibility-weighted (SWI), and resting-state functional imaging modalities. Here, we described the contents of these different neuroimaging datasets and the processing pipelines used to derive brain phenotypes, as well as how quality control was assessed. In addition, we present preliminary results on associations of some of these brain image-derived phenotypes at the whole brain level with both age and sex, in the subsample of 1722 individuals aged less than 26 years. We demonstrate that the post-adolescence period is characterized by changes in both structural and microstructural brain phenotypes. Grey matter cortical thickness, surface area and volume were found to decrease with age, while white matter volume shows increase. Diffusivity, either radial or axial, was found to robustly decrease with age whereas fractional anisotropy only slightly increased. As for the neurite orientation dispersion and densities, both were found to increase with age. The isotropic volume fraction also showed a slight increase with age. These preliminary findings emphasize the complexity of changes in brain structure and function occurring in this critical period at the interface of late maturation and early ageing.
dc.description.sponsorshipLaboratoire pour les applications en imagerie biomédicaleen_US
dc.language.isoENen_US
dc.subject.enMRI
dc.subject.enBrain
dc.subject.enStudent
dc.subject.enCohort
dc.subject.enCross-sectional
dc.subject.enPost-adolescence
dc.title.enThe MRi-Share database: brain imaging in a cross-sectional cohort of 1870 university students
dc.typeArticle de revueen_US
dc.identifier.doi10.1007/s00429-021-02334-4en_US
dc.subject.halSciences du Vivant [q-bio]/Santé publique et épidémiologieen_US
dc.identifier.pubmed34283296en_US
bordeaux.journalBrain Structure & Functionen_US
bordeaux.page2057-2085en_US
bordeaux.volume226en_US
bordeaux.hal.laboratoriesBordeaux Population Health Research Center (BPH) - UMR 1219en_US
bordeaux.institutionUniversité de Bordeauxen_US
bordeaux.institutionINSERMen_US
bordeaux.teamVINTAGEen_US
bordeaux.peerReviewedouien_US
bordeaux.inpressnonen_US
bordeaux.identifier.funderIDConseil Régional Aquitaineen_US
bordeaux.identifier.funderIDEuropean Research Councilen_US
bordeaux.identifier.funderIDH2020 European Research Councilen_US
bordeaux.identifier.funderIDFondation pour la Recherche Médicaleen_US
hal.identifierhal-03328730
hal.version1
hal.date.transferred2021-08-30T10:05:56Z
hal.exporttrue
dc.rights.ccPas de Licence CCen_US
bordeaux.COinSctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=Brain%20Structure%20&%20Function&rft.date=2021-07-20&rft.volume=226&rft.spage=2057-2085&rft.epage=2057-2085&rft.eissn=1863-2653&rft.issn=1863-2653&rft.au=TSUCHIDA,%20Ami&LAURENT,%20Alexandre&CRIVELLO,%20Fabrice&PETIT,%20Laurent&JOLIOT,%20Marc&rft.genre=article


Fichier(s) constituant ce document

FichiersTailleFormatVue

Il n'y a pas de fichiers associés à ce document.

Ce document figure dans la(les) collection(s) suivante(s)

Afficher la notice abrégée