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Functional abdominal pain disorders and patient- and parent- reported outcomes in children with inflammatory bowel disease in remission

dc.rights.licenseopenen_US
dc.contributor.authorTRAN, Lea Chantal
dc.contributor.authorBRIDOUX-HENNO, Laure
dc.contributor.authorGASTINEAU, Swellen
dc.contributor.authorDABADIE, Alain
dc.contributor.authorCARRE, Emilie
dc.contributor.authorHUGOT, Jean-Pierre
dc.contributor.authorMARTINEZ-VINSON, Christine
dc.contributor.authorMOSCA, Alexis
dc.contributor.authorCOOPMAN, Stephanie
hal.structure.identifierBordeaux population health [BPH]
dc.contributor.authorLAMIREAU, Thierry
dc.contributor.authorENAUD, Raphael
dc.contributor.authorCLOUZEAU, Haude
dc.contributor.authorBERTRAND, Valerie
dc.contributor.authorPIGNEUR, Benedicte
dc.contributor.authorRUEMMELE, Frank
dc.contributor.authorDEGAS, Vanessa
dc.contributor.authorBRETON, Anne
dc.contributor.authorMAS, Emmanuel
dc.contributor.authorLACOTTE, Edouard
dc.contributor.authorCHAILLOU-LEGAULT, Emilie
dc.contributor.authorCARON, Nicolas
dc.contributor.authorLANGUEPIN, Jane
dc.contributor.authorWILLOT, Stephanie
dc.contributor.authorBOUAZZA, Ahlem
dc.contributor.authorSPYCKERELLE, Claire
dc.contributor.authorDIMITROV, Georges
dc.contributor.authorTHOMASSIN, Nadege
dc.contributor.authorDJEDDI, Djamal
dc.contributor.authorVANRENTERGHEM, Audrey
dc.contributor.authorGRANDJEAN, Camille
dc.contributor.authorVIALA, Jerome
dc.contributor.authorDUPONT-LUCAS, Claire
dc.date.accessioned2021-08-24T10:11:36Z
dc.date.available2021-08-24T10:11:36Z
dc.date.issued2021-06-26
dc.identifier.issn1590-8658en_US
dc.identifier.urihttps://oskar-bordeaux.fr/handle/20.500.12278/110205
dc.description.abstractEnBACKGROUND: Chronic abdominal pain occurs frequently in pediatric patients with inflammatory bowel disease (IBD) in remission. AIMS: To assess the prevalence and factors associated with Functional Abdominal Pain Disorders among IBD children in remission (IBD-FAPD). METHODS: Patients with IBD for > 1 year, in clinical remission for ≥ 3 months were recruited from a National IBD network. IBD-FAPDs were assessed using the Rome III questionnaire criteria. Patient- or parent- reported outcomes were assessed. RESULTS: Among 102 included patients, 57 (56%) were boys, mean age (DS) was 15.0 (± 2.0) years and 75 (74%) had Crohn's disease. Twenty-two patients (22%) had at least one Functional Gastrointestinal Disorder among which 17 had at least one IBD-FAPD. Past severity of disease or treatments received and level of remission were not significantly associated with IBD-FAPD. Patients with IBD-FAPD reported more fatigue (peds-FACIT-F: 35.9 ± 9.8 vs. 43.0 ± 6.9, p = 0.01) and a lower HR-QoL (IMPACT III: 76.5 ± 9.6 vs. 81.6 ± 9.2, p = 0.04) than patients without FAPD, and their parents had higher levels of State and Trait anxiety than the other parents. CONCLUSIONS: Prevalence of IBD-FAPD was 17%. IBD-FAPD was not associated with past severity of disease, but with fatigue and lower HR-QoL.
dc.language.isoENen_US
dc.rightsAttribution 3.0 United States*
dc.rights.urihttp://creativecommons.org/licenses/by/3.0/us/*
dc.subject.enFatigue
dc.subject.enQuality-of-life
dc.subject.enAnxiety
dc.subject.enPaediatrics
dc.subject.enAbdominal pain
dc.subject.enInflammatory bowel disease
dc.title.enFunctional abdominal pain disorders and patient- and parent- reported outcomes in children with inflammatory bowel disease in remission
dc.typeArticle de revueen_US
dc.identifier.doi10.1016/j.dld.2021.05.034en_US
dc.subject.halSciences du Vivant [q-bio]/Santé publique et épidémiologieen_US
dc.identifier.pubmed34187767en_US
bordeaux.journalDigestive and Liver Diseaseen_US
bordeaux.hal.laboratoriesBordeaux Population Health Research Center (BPH) - UMR 1219en_US
bordeaux.institutionUniversité de Bordeauxen_US
bordeaux.institutionINSERMen_US
bordeaux.teamLEHA_BPH
bordeaux.peerReviewedouien_US
bordeaux.inpressnonen_US
hal.identifierhal-03325068
hal.version1
hal.date.transferred2021-08-24T10:11:41Z
hal.exporttrue
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