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dc.rights.licenseopenen_US
dc.contributor.authorROUX, Barbara
dc.contributor.authorBERTHOU-CONTRERAS, Julie
dc.contributor.authorBEUSCART, Jean-Baptiste
dc.contributor.authorCHARENTON-BLAVIGNAC, Marion
dc.contributor.authorDOUCET, Jean
dc.contributor.authorFOURNIER, Jean-Pascal
dc.contributor.authorDE LA GASTINE, Blandine
dc.contributor.authorGAUTIER, Sophie
dc.contributor.authorGONTHIER, Regis
dc.contributor.authorGRAS, Valerie
dc.contributor.authorGRAU, Muriel
hal.structure.identifierBordeaux population health [BPH]
dc.contributor.authorNOIZE, Pernelle
dc.contributor.authorPOLARD, Elisabeth
dc.contributor.authorRUDELLE, Karen
dc.contributor.authorVALNET-RABIER, Marie-Blanche
dc.contributor.authorTANNOU, Thomas
dc.contributor.authorLAROCHE, Marie-Laure
dc.date.accessioned2021-08-24T08:34:18Z
dc.date.available2021-08-24T08:34:18Z
dc.date.issued2021-06-11
dc.identifier.issn0031-6970en_US
dc.identifier.urihttps://oskar-bordeaux.fr/handle/20.500.12278/110198
dc.description.abstractEnPURPOSE: To establish a consensus on both explicit and implicit criteria in order to identify potentially inappropriate prescribing (PIP) in French older people aged 75 years and over or 65 years and over with multimorbidity. METHODS: Fifteen experts in geriatrics, general practice, pharmacy, and clinical pharmacology were involved in a two-round Delphi survey to assess preliminary explicit and implicit criteria based on an extensive literature review and up-to-date evidence data. Experts were asked to rate their level of agreement using a 5-level Likert scale for inclusion of criteria and also for rationale and therapeutic alternatives. A consensus was considered as reached if at least 75% of the experts rated criteria as "strongly agreed" or "agreed." RESULTS: The new tool included a seven-step algorithm (implicit criteria) encompassing the three main domains that define PIP (i.e. overprescribing, underprescribing, and misprescribing) and 104 explicit criteria. Explicit criteria were divided into 6 tables related to inappropriate drug duplications (n = 7 criteria), omissions of medications and/or medication associations (n = 16), medications with an unfavourable benefit/risk ratio and/or a questionable efficacy (n = 39), medications with an unsuitable dose (n = 4) or duration (n = 6), drug-disease (n = 13), and drug-drug interactions (n = 19). CONCLUSION: The REMEDI[e]S tool (REview of potentially inappropriate MEDIcation pr[e]scribing in Seniors) is an original mixed tool, adapted to French medical practices, aimed at preventing PIP both at the individual level in clinical practice and the population level in large-scale studies. Therefore, its use could contribute to an improvement in healthcare professionals' prescribing practices and safer care in older adults.
dc.language.isoENen_US
dc.subject.enOlder adults
dc.subject.enInappropriate prescribing
dc.subject.enImplicit criteria
dc.subject.enExplicit criteria
dc.subject.enDelphi method
dc.subject.enFrance
dc.title.enREview of potentially inappropriate MEDIcation pr[e]scribing in Seniors (REMEDI[e]S): French implicit and explicit criteria
dc.typeArticle de revueen_US
dc.identifier.doi10.1007/s00228-021-03145-6en_US
dc.subject.halSciences du Vivant [q-bio]/Santé publique et épidémiologieen_US
dc.identifier.pubmed34115158en_US
bordeaux.journalEuropean Journal of Clinical Pharmacologyen_US
bordeaux.hal.laboratoriesBordeaux Population Health Research Center (BPH) - UMR 1219en_US
bordeaux.institutionUniversité de Bordeauxen_US
bordeaux.institutionINSERMen_US
bordeaux.teamPharmacoEpi-Drugsen_US
bordeaux.peerReviewedouien_US
bordeaux.inpressnonen_US
hal.exportfalse
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