Ambulatory drug changes in the elderly after hospital discharge: A cohort study
| dc.rights.license | open | en_US |
| dc.contributor.author | ROUSSELOT, Nicolas | |
| dc.contributor.author | JOSEPH, Jean-Philippe | |
| hal.structure.identifier | Bordeaux population health [BPH] | |
| dc.contributor.author | NOIZE, Pernelle | |
| dc.contributor.author | BERDAI, Driss | |
| hal.structure.identifier | Bordeaux population health [BPH] | |
| dc.contributor.author | FOURRIER-REGLAT, Annie | |
| hal.structure.identifier | Bordeaux population health [BPH] | |
| dc.contributor.author | BOSCO-LEVY, Pauline | |
| dc.date.accessioned | 2021-07-08T11:36:53Z | |
| dc.date.available | 2021-07-08T11:36:53Z | |
| dc.date.issued | 2021-05-05 | |
| dc.identifier.issn | 0040-5957 | en_US |
| dc.identifier.uri | https://oskar-bordeaux.fr/handle/20.500.12278/106463 | |
| dc.description.abstractEn | AIM: To describe the ambulatory changes in drug prescriptions 3 months after hospital discharge among elderly patients aged 75 and over, and to identify the reasons for these changes. METHODS: A prospective cohort study was conducted on subjects, discharged between 09/2016 and 01/2017 from the Bordeaux University Hospital. Prescription forms were collected from patients' pharmacists. The main outcome was the occurrence of at least one significant change (SC) defined as an initiation, a discontinuation, a switch or change in drug daily dosage as regards the drugs prescribed upon hospital discharge and those prescribed 3 months after. Whenever drug SC occurred, general practitioners were requested to elicit reasons for such changes. RESULTS: Among the 126 patients included in our study, 73 underwent a 3-month follow-up period, without death or being re-hospitalised. 87.7% of them had at least one SC 3 months after discharge, with an average of 3.1±2.5 SC per patient. Main changes involved: discontinuation or dose decrease of anxiolytics, hypnotics, antalgics, betablockers and calcium channel blockers; start or dose increase of diuretics, ACE inhibitors and angiotensin receptor blockers. In patients with a 3-month follow-up period, 27.4% underwent at least one ADR-induced SC. CONCLUSION: Most elderly patients experience drug prescription changes after discharge. Some, according to drug iatrogenic, could be avoided through better cooperation between hospital and ambulatory prescribers. | |
| dc.language.iso | EN | en_US |
| dc.subject.en | General practice | |
| dc.subject.en | Patient discharge | |
| dc.subject.en | Elderly | |
| dc.subject.en | Drug prescriptions | |
| dc.subject.en | Continuity of patient care | |
| dc.subject.en | Cohort studies | |
| dc.title.en | Ambulatory drug changes in the elderly after hospital discharge: A cohort study | |
| dc.type | Article de revue | en_US |
| dc.identifier.doi | 10.1016/j.therap.2021.04.015 | en_US |
| dc.subject.hal | Sciences du Vivant [q-bio]/Santé publique et épidémiologie | en_US |
| dc.identifier.pubmed | 34045080 | en_US |
| bordeaux.journal | Thérapie | en_US |
| bordeaux.hal.laboratories | Bordeaux Population Health Research Center (BPH) - UMR 1219 | en_US |
| bordeaux.institution | Université de Bordeaux | en_US |
| bordeaux.institution | INSERM | en_US |
| bordeaux.team | MORPH3Eus | en_US |
| bordeaux.team | PharmacoEpi-Drugs | en_US |
| bordeaux.peerReviewed | oui | en_US |
| bordeaux.inpress | non | en_US |
| hal.identifier | hal-03281639 | |
| hal.version | 1 | |
| hal.date.transferred | 2021-07-08T11:36:57Z | |
| hal.export | true | |
| bordeaux.COinS | ctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=Th%C3%A9rapie&rft.date=2021-05-05&rft.eissn=0040-5957&rft.issn=0040-5957&rft.au=ROUSSELOT,%20Nicolas&JOSEPH,%20Jean-Philippe&NOIZE,%20Pernelle&BERDAI,%20Driss&FOURRIER-REGLAT,%20Annie&rft.genre=article |
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