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No effect of test and treat on sexual behaviours at population level in rural South Africa
| dc.rights.license | open | en_US |
| hal.structure.identifier | Bordeaux population health [BPH] | |
| dc.contributor.author | ROLLAND, Matthieu | |
| dc.contributor.author | MCGRATH, N. | |
| hal.structure.identifier | Bordeaux population health [BPH] | |
| dc.contributor.author | TIENDREBEOGO, Kiswend-Sida Thierry | |
| dc.contributor.author | LARMARANGE, J. | |
| dc.contributor.author | PILLAY, D. | |
| hal.structure.identifier | Bordeaux population health [BPH] | |
| dc.contributor.author | DABIS, Francois | |
| hal.structure.identifier | Bordeaux population health [BPH] | |
| dc.contributor.author | ORNE-GLIEMANN, Joanna | |
| dc.date.accessioned | 2020-07-10T10:16:33Z | |
| dc.date.available | 2020-07-10T10:16:33Z | |
| dc.date.issued | 2019-03-15 | |
| dc.identifier.issn | 1473-5571 (Electronic) 0269-9370 (Linking) | en_US |
| dc.identifier.uri | https://oskar-bordeaux.fr/handle/20.500.12278/10404 | |
| dc.description.abstractEn | CONTEXT: Within the community-randomised ANRS 12249 Treatment-as-Prevention (TasP) trial conducted in rural South Africa, we analysed sexual behaviours stratified by sex over time, comparing immediate ART irrespective of CD4 count vs CD4-guided ART (start at CD4>350 then >500) arms. METHODS: As part of the 6-monthly home-based trial rounds, a sexual behaviour questionnaire (IQ) was administered to all residents >/=16 years. We considered seven indicators: sexual intercourse in the past month; at least one regular sexual partner in the past six months; at least one casual sexual partner in the past six months and more than one sexual partner in the past six months; condom use at last sex (CLS) with regular partner, CLS with casual partner, and point prevalence estimate of concurrency. We conducted repeated cross-sectional analyses, stratified by sex. GEE models were used, including trial arm, trial time, calendar time and interaction between trial arm and trial time. RESULTS: CLS with regular partner varied between 29%-51% and 23%- 46% for men and women, respectively, with significantly lower odds among women in the control versus intervention arm by trial end (p < 0.001). CLS with casual partner among men showed a significant interaction between arm and trial round, with no consistent pattern. Women declared more than one partner in the past 6 months in less that 1% of IQs; among men, rates varied between 5%-12%, and odds significantly and continuously declined between calendar rounds 1 and 7 (OR = 4.2 [3.24-5.45]). CONCLUSION: Universal Test and Treat was not associated with increased sexual risk behaviours. | |
| dc.language.iso | EN | en_US |
| dc.subject.en | IDLIC | |
| dc.subject.en | ANRS 12249 TaSP | |
| dc.title.en | No effect of test and treat on sexual behaviours at population level in rural South Africa | |
| dc.title.alternative | Aids | en_US |
| dc.type | Article de revue | en_US |
| dc.identifier.doi | 10.1097/QAD.0000000000002104 | en_US |
| dc.subject.hal | Sciences du Vivant [q-bio]/Santé publique et épidémiologie | en_US |
| dc.identifier.pubmed | 30608273 | en_US |
| bordeaux.journal | AIDS. Official journal of the international AIDS Society | en_US |
| bordeaux.page | 709-722 | en_US |
| bordeaux.volume | 33 | en_US |
| bordeaux.hal.laboratories | Bordeaux Population Health Research Center (BPH) - UMR 1219 | en_US |
| bordeaux.issue | 4 | en_US |
| bordeaux.institution | Université de Bordeaux | en_US |
| bordeaux.peerReviewed | oui | en_US |
| bordeaux.inpress | non | en_US |
| bordeaux.identifier.funderID | Agence Nationale de Recherches sur le Sida et les Hépatites Virales | en_US |
| hal.identifier | hal-03162644 | |
| hal.version | 1 | |
| hal.date.transferred | 2021-03-08T14:51:37Z | |
| hal.export | true | |
| bordeaux.COinS | ctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=AIDS.%20Official%20journal%20of%20the%20international%20AIDS%20Society&rft.date=2019-03-15&rft.volume=33&rft.issue=4&rft.spage=709-722&rft.epage=709-722&rft.eissn=1473-5571%20(Electronic)%200269-9370%20(Linking)&rft.issn=1473-5571%20(Electronic)%200269-9370%20(Linking)&rft.au=ROLLAND,%20Matthieu&MCGRATH,%20N.&TIENDREBEOGO,%20Kiswend-Sida%20Thierry&LARMARANGE,%20J.&PILLAY,%20D.&rft.genre=article |
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