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Educational intervention to improve the knowledge, attitude and practice of healthcare professionals regarding pharmacovigilance in South-South Nigeria
| dc.rights.license | open | en_US |
| dc.contributor.author | OPADEYI, A. O. | |
| hal.structure.identifier | Bordeaux population health [BPH] | |
| dc.contributor.author | FOURRIER-REGLAT, Annie | |
| dc.contributor.author | ISAH, A. O. | |
| dc.date.accessioned | 2020-07-09T09:52:27Z | |
| dc.date.available | 2020-07-09T09:52:27Z | |
| dc.date.issued | 2019-02 | |
| dc.identifier.issn | 2042-0986 (Print) 2042-0994 (Online) | en_US |
| dc.identifier.uri | https://oskar-bordeaux.fr/handle/20.500.12278/10270 | |
| dc.description.abstractEn | Background: Our aim in this study was to evaluate the effect of a combined educational intervention and year-long monthly text message reinforcements via the Short Messaging System (SMS) on the knowledge, attitude and practice (KAP) of healthcare professionals (HCPs) towards pharmacovigilance. Methods: Six randomly selected teaching hospitals in the South-South zone of Nigeria were randomized in 1:1 ratio into intervention and control groups. The educational intervention consisted of delivering a seminar followed by sending monthly texts message reinforcements via SMS over 12 months. Then a semi-structured questionnaire regarding the KAP of pharmacovigilance was completed by HCPs working in the hospitals after the intervention. Data was analysed descriptively and inferentially. Results: A total of 931 HCPs participated in the post intervention study (596 in the intervention and 335 in the control). The M:F ratio was 1:1.5. According to the KAP questionnaire, a significant difference was observed between the intervention and control groups, regarding knowledge of the types of adverse drug reactions (ADRs). ADR resulting from pharmacological action of the drug (85.6% versus 77%, p = 0.001), the fact that ADRs can persist for a long time; (60.1% versus 53.4%, p = 0.024) and a higher awareness of the ADR reporting form (48.7% versus 18.8%, p < 0.001). Most respondents in the intervention group (68.5% versus 60.6%, p = 0.001) believed they should report ADRs even if they were unsure an ADR has occurred, a greater proportion of HCPs from the intervention group had significantly observed an ADR (82% versus 73.4%, p = 0.001). Furthermore, of the 188 who had ever reported an ADR, 41% from the intervention group used the national ADR reporting form compared with 19.8% from the controls (p < 0.001). Conclusion: This educational intervention and the use of SMS as a reinforcement tool appeared to have positively impacted on the knowledge and practice of pharmacovigilance in South-South Nigeria with a less-than-impressive change in attitude. Continuous medical education may be required to effect long-lasting changes. | |
| dc.language.iso | EN | en_US |
| dc.rights | Attribution-NonCommercial 3.0 United States | |
| dc.rights.uri | https://creativecommons.org/licenses/by-nc/3.0/us/ | |
| dc.subject.en | PharmacoEpi-Drugs | |
| dc.subject.en | CIC1401 | |
| dc.title.en | Educational intervention to improve the knowledge, attitude and practice of healthcare professionals regarding pharmacovigilance in South-South Nigeria | |
| dc.title.alternative | Ther Adv Drug Saf | en_US |
| dc.type | Article de revue | en_US |
| dc.identifier.doi | 10.1177/2042098618816279 | en_US |
| dc.subject.hal | Sciences du Vivant [q-bio]/Santé publique et épidémiologie | en_US |
| dc.identifier.pubmed | 30719280 | en_US |
| bordeaux.journal | Therapeutic Advances in Drug Safety | en_US |
| bordeaux.page | 2042098618816279 | en_US |
| bordeaux.volume | 10 | en_US |
| bordeaux.hal.laboratories | Bordeaux Population Health Research Center (BPH) - UMR 1219 | en_US |
| bordeaux.institution | Université de Bordeaux | en_US |
| bordeaux.peerReviewed | oui | en_US |
| bordeaux.inpress | non | en_US |
| hal.identifier | hal-03285323 | |
| hal.version | 1 | |
| hal.date.transferred | 2021-07-13T09:35:24Z | |
| hal.export | true | |
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