Mostrar el registro sencillo del ítem

An experimental chemical reactor for peptide formation, elongation and accumulation on the Primitive Earth

hal.structure.identifierInstitut des Biomolécules Max Mousseron [Pôle Chimie Balard] [IBMM]
hal.structure.identifierPhysique des interactions ioniques et moléculaires [PIIM]
dc.contributor.authorDANGER, Grégoire
hal.structure.identifierLaboratoire d'Astrophysique de Bordeaux [Pessac] [LAB]
hal.structure.identifierObservatoire aquitain des sciences de l'univers [OASU]
hal.structure.identifierUniversité Sciences et Technologies - Bordeaux 1 [UB]
hal.structure.identifierLaboratoire d'astrodynamique, d'astrophysique et d'aéronomie de bordeaux [L3AB]
dc.contributor.authorDOBRIJEVIC, M.
hal.structure.identifierLaboratoire d'Astrophysique de Bordeaux [Pessac] [LAB]
hal.structure.identifierObservatoire aquitain des sciences de l'univers [OASU]
hal.structure.identifierUniversité Sciences et Technologies - Bordeaux 1 [UB]
hal.structure.identifierLaboratoire d'astrodynamique, d'astrophysique et d'aéronomie de bordeaux [L3AB]
dc.contributor.authorSELSIS, Franck
hal.structure.identifierLaboratoire d'Astrophysique de Bordeaux [Pessac] [LAB]
hal.structure.identifierObservatoire aquitain des sciences de l'univers [OASU]
hal.structure.identifierUniversité Sciences et Technologies - Bordeaux 1 [UB]
hal.structure.identifierLaboratoire d'astrodynamique, d'astrophysique et d'aéronomie de bordeaux [L3AB]
dc.contributor.authorHÉBRARD, Eric
dc.contributor.authorHENDECOURT, Louis D.
hal.structure.identifierInstitut des Biomolécules Max Mousseron [Pôle Chimie Balard] [IBMM]
dc.contributor.authorPASCAL, Robert
dc.date.issued2010
dc.date.conference2010
dc.description.abstractEnIn this contribution, starting from a set of molecules that could have been available on the early earth, we will present a chemical reactor capable of promoting amino acid activation and condensation, for their elongation into oligopeptides allowing the accumulation of peptide chains in environments considered as prebiotic. Organic matter available on the early Earth may have two origins. The first reservoir of material derived from exogenous inputs that correspond to organic compounds brought to the Earth via comets or (micro-) meteorites. A second pool of organic matter was available from the atmosphere of the primitive Earth, in which photochemistry or processes induced by lightning can have led to low-molecular weight chemical intermediates of interest for the development of further prebiotic chemistry under favorable conditions. This kind of chemistry may have been present at certain stages of the evolution of the surface (atmosphere/ocean) of the Earth, some 3.5 to 4 billion years ago. One of our aims is to identify new chemical pathways allowing the formation of oligopeptides under prebiotic conditions starting from these two reservoirs of organic matter. Our initial studies have identified several possible pathways leading to peptide formations either under oxidizing conditions (with assistance of oxides of nitrogen) or under reductive ones, with cyanic acid and cyanate (or its precursor urea) and amino acids as only required starting materials. Through these reactions, amino acids are activated and condensed into oligopeptides which once formed, elongate from their N-terminal residue. We have subsequently shown that under certain conditions the amino terminus can react with cyanic acid which limits peptide elongation to short peptide chains. To overcome these limitations to peptide elongations, reagents could be available within the above mentioned reservoirs to enable elongation no longer at the N-terminal residues, but at C-terminal residues through a C-terminal activation.
dc.language.isoen
dc.source.title38th COSPAR Scientific Assembly. Held 18-15 July 2010, in Bremen, Germany, p.7 - 2010
dc.title.enAn experimental chemical reactor for peptide formation, elongation and accumulation on the Primitive Earth
dc.typeCommunication dans un congrès
dc.subject.halPlanète et Univers [physics]/Astrophysique [astro-ph]/Planétologie et astrophysique de la terre [astro-ph.EP]
dc.subject.halPhysique [physics]/Astrophysique [astro-ph]/Planétologie et astrophysique de la terre [astro-ph.EP]
bordeaux.page3255
bordeaux.volume38
bordeaux.conference.title38th COSPAR Scientific Assembly
bordeaux.countryDE
bordeaux.title.proceeding38th COSPAR Scientific Assembly. Held 18-15 July 2010, in Bremen, Germany, p.7 - 2010
bordeaux.conference.citybremen
bordeaux.peerReviewedoui
hal.identifierhal-00572370
hal.version1
hal.invitednon
hal.proceedingsoui
hal.popularnon
hal.audienceInternationale
hal.origin.linkhttps://hal.archives-ouvertes.fr//hal-00572370v1
bordeaux.COinSctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.btitle=38th%20COSPAR%20Scientific%20Assembly.%20Held%2018-15%20July%202010,%20in%20Bremen,%20Germany,%20p.7%20-%202010&rft.date=2010&rft.volume=38&rft.spage=3255&rft.epage=3255&rft.au=DANGER,%20Gr%C3%A9goire&DOBRIJEVIC,%20M.&SELSIS,%20Franck&H%C3%89BRARD,%20Eric&HENDECOURT,%20Louis%20D.&rft.genre=unknown


Archivos en el ítem

ArchivosTamañoFormatoVer

No hay archivos asociados a este ítem.

Este ítem aparece en la(s) siguiente(s) colección(ones)

Mostrar el registro sencillo del ítem