Mostrar el registro sencillo del ítem

Predictors of hospital discharge and mortality in patients with diabetes and COVID-19: updated results from the nationwide CORONADO study

dc.rights.licenseopenen_US
dc.contributor.authorWARGNY, Matthieu
dc.contributor.authorPOTIER, Louis
dc.contributor.authorGOURDY, Pierre
dc.contributor.authorPICHELIN, M.
dc.contributor.authorMATTHIEU, C.
dc.contributor.authorBENHAMOU, Pierre-Yves
dc.contributor.authorBONNET, Jean-Baptiste
dc.contributor.authorBORDIER, Lyse
dc.contributor.authorBOURRON, Olivier
dc.contributor.authorCHAUMEIL, Claude
dc.contributor.authorCHEVALIER, Nicolas
dc.contributor.authorDARMON, Patrice
dc.contributor.authorDELENNE, Blandine
dc.contributor.authorDEMARSY, Delphine
dc.contributor.authorDUMAS, Marie
dc.contributor.authorDUPUY, Olivier
dc.contributor.authorFLAUS-FURMANIUK, Anna
dc.contributor.authorGAUTIER, Jean-Francois
dc.contributor.authorGUEDJ, Anne-Marie
dc.contributor.authorJEANDIDIER, Nathalie
dc.contributor.authorLARGER, Etienne
dc.contributor.authorLE BERRE, Jean-Philippe
dc.contributor.authorLUNGO, Myriam
dc.contributor.authorMONTANIER, Nathanaelle
dc.contributor.authorMOULIN, Philippe
dc.contributor.authorPLAT, Francoise
hal.structure.identifierBordeaux population health [BPH]
dc.contributor.authorRIGALLEAU, Vincent
dc.contributor.authorROBERT, Rene
dc.contributor.authorSERET-BEGUE, Dominique
dc.contributor.authorSERUSCLAT, Pierre
dc.contributor.authorSMATI, Sarra
dc.contributor.authorTHEBAUT, Jean-Francois
dc.contributor.authorTRAMUNT, Blandine
dc.contributor.authorVATIER, Camille
dc.contributor.authorVELAYOUDOM, Fritz-Line
dc.contributor.authorVERGES, Bruno
dc.contributor.authorWINISZEWSKI, Patrice
dc.contributor.authorZABULON, Audrey
dc.contributor.authorGOURRAUD, Pierre-Antoine
dc.contributor.authorROUSSEL, Ronan
dc.contributor.authorCARIOU, Bertrand
dc.contributor.authorHADJADJ, Samy
dc.date.accessioned2021-06-30T10:23:57Z
dc.date.available2021-06-30T10:23:57Z
dc.date.issued2021-04
dc.identifier.issn0012-186X (Print) 0012-186xen_US
dc.identifier.urihttps://oskar-bordeaux.fr/handle/20.500.12278/94940
dc.description.abstractEnAIMS/HYPOTHESIS: This is an update of the results from the previous report of the CORONADO (Coronavirus SARS-CoV-2 and Diabetes Outcomes) study, which aims to describe the outcomes and prognostic factors in patients with diabetes hospitalised for coronavirus disease-2019 (COVID-19). METHODS: The CORONADO initiative is a French nationwide multicentre study of patients with diabetes hospitalised for COVID-19 with a 28-day follow-up. The patients were screened after hospital admission from 10 March to 10 April 2020. We mainly focused on hospital discharge and death within 28 days. RESULTS: We included 2796 participants: 63.7% men, mean age 69.7 ± 13.2 years, median BMI (25th-75th percentile) 28.4 (25.0-32.4) kg/m(2). Microvascular and macrovascular diabetic complications were found in 44.2% and 38.6% of participants, respectively. Within 28 days, 1404 (50.2%; 95% CI 48.3%, 52.1%) were discharged from hospital with a median duration of hospital stay of 9 (5-14) days, while 577 participants died (20.6%; 95% CI 19.2%, 22.2%). In multivariable models, younger age, routine metformin therapy and longer symptom duration on admission were positively associated with discharge. History of microvascular complications, anticoagulant routine therapy, dyspnoea on admission, and higher aspartate aminotransferase, white cell count and C-reactive protein levels were associated with a reduced chance of discharge. Factors associated with death within 28 days mirrored those associated with discharge, and also included routine treatment by insulin and statin as deleterious factors. CONCLUSIONS/INTERPRETATION: In patients with diabetes hospitalised for COVID-19, we established prognostic factors for hospital discharge and death that could help clinicians in this pandemic period. TRIAL REGISTRATION: Clinicaltrials.gov identifier: NCT04324736.
dc.language.isoENen_US
dc.rightsAttribution 3.0 United States*
dc.rights.urihttp://creativecommons.org/licenses/by/3.0/us/*
dc.subject.enAdmission plasma glucose
dc.subject.enCOVID-19
dc.subject.enDeath
dc.subject.enDiabetes
dc.subject.enDischarge
dc.subject.enHbA1c
dc.subject.enHome discharge
dc.subject.enMechanical ventilation
dc.title.enPredictors of hospital discharge and mortality in patients with diabetes and COVID-19: updated results from the nationwide CORONADO study
dc.typeArticle de revueen_US
dc.identifier.doi10.1007/s00125-020-05351-wen_US
dc.subject.halSciences du Vivant [q-bio]/Santé publique et épidémiologieen_US
dc.identifier.pubmed33599800en_US
bordeaux.journalDiabetologiaen_US
bordeaux.page778-794en_US
bordeaux.volume64en_US
bordeaux.hal.laboratoriesBordeaux Population Health Research Center (BPH) - UMR 1219en_US
bordeaux.issue4en_US
bordeaux.institutionUniversité de Bordeauxen_US
bordeaux.institutionINSERMen_US
bordeaux.teamLEHA_BPH
bordeaux.peerReviewedouien_US
bordeaux.inpressnonen_US
bordeaux.identifier.funderIDSociété Francophone du Diabèteen_US
bordeaux.identifier.funderIDCentre Hospitalier Universitaire de Nantesen_US
hal.exportfalse
bordeaux.COinSctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=Diabetologia&rft.date=2021-04&rft.volume=64&rft.issue=4&rft.spage=778-794&rft.epage=778-794&rft.eissn=0012-186X%20(Print)%200012-186x&rft.issn=0012-186X%20(Print)%200012-186x&rft.au=WARGNY,%20Matthieu&POTIER,%20Louis&GOURDY,%20Pierre&PICHELIN,%20M.&MATTHIEU,%20C.&rft.genre=article


Archivos en el ítem

Thumbnail
Nombre:
BPH_Diabetologia_2021_Wargny.pdf
Tamaño:
1007.Kb
Formato:
PDF
Ver/Abrir
Thumbnail
Nombre:
license_rdf
Tamaño:
914bytes
Formato:
application/rdf+xml
Ver/Abrir

Este ítem aparece en la(s) siguiente(s) colección(ones)

Mostrar el registro sencillo del ítem