Mostrar el registro sencillo del ítem

Large International Validation of ABSIS and PDAI Pemphigus Severity Scores

dc.rights.licenseopenen_US
dc.contributor.authorHEBERT, V.
dc.contributor.authorBOULARD, C.
hal.structure.identifierBordeaux population health [BPH]
dc.contributor.authorHOUIVET, Estelle
dc.contributor.authorDUVERT LEHEMBRE, S.
dc.contributor.authorBORRADORI, L.
dc.contributor.authorDELLA TORRE, R.
dc.contributor.authorFELICIANI, C.
dc.contributor.authorFANIA, L.
dc.contributor.authorZAMBRUNO, G.
dc.contributor.authorCAMAIONI, D. B.
dc.contributor.authorDIDONA, B.
dc.contributor.authorMARINOVIC, B.
dc.contributor.authorSCHMIDT, E.
dc.contributor.authorSCHUMACHER, N.
dc.contributor.authorHUNEFELD, C.
dc.contributor.authorSCHANZ, S.
dc.contributor.authorKERN, J. S.
dc.contributor.authorHOFMANN, S.
hal.structure.identifierBordeaux population health [BPH]
dc.contributor.authorBOUYEURE, Anne Charlotte
dc.contributor.authorPICARD-DAHAN, C.
dc.contributor.authorPROST-SQUARCIONI, C.
dc.contributor.authorCAUX, F.
dc.contributor.authorALEXANDRE, M.
dc.contributor.authorINGEN-HOUSZ-ORO, S.
dc.contributor.authorBAGOT, M.
dc.contributor.authorTANCREDE-BOHIN, E.
dc.contributor.authorBOUAZIZ, J. D.
dc.contributor.authorFRANCK, N.
dc.contributor.authorVABRES, P.
dc.contributor.authorLABEILLE, B.
dc.contributor.authorRICHARD, M. A.
dc.contributor.authorDELAPORTE, E.
dc.contributor.authorDUPUY, A.
dc.contributor.authorD'INCAN, M.
dc.contributor.authorQUEREUX, G.
dc.contributor.authorSKOWRO, F.
dc.contributor.authorPAUL, C.
dc.contributor.authorLIVIDEANU, C. B.
dc.contributor.authorBEYLOT-BARRY, M.
dc.contributor.authorDOUTRE, M. S.
dc.contributor.authorAVENEL-AUDRAN, M.
dc.contributor.authorBEDANE, C.
dc.contributor.authorBERNARD, P.
dc.contributor.authorMACHET, L.
dc.contributor.authorMAILLARD, H.
dc.contributor.authorJULLIEN, D.
dc.contributor.authorDEBARBIEUX, S.
dc.contributor.authorSASSOLAS, B.
dc.contributor.authorMISERY, L.
dc.contributor.authorABASQ, C.
dc.contributor.authorDEREURE, O.
hal.structure.identifierBordeaux population health [BPH]
dc.contributor.authorLAGOUTTE, Philippe
dc.contributor.authorFERRANTI, V.
dc.contributor.authorWERTH, V. P.
dc.contributor.authorMURRELL, D. F.
dc.contributor.authorHERTL, M.
hal.structure.identifierBordeaux population health [BPH]
dc.contributor.authorBENICHOU, Jacques
dc.contributor.authorJOLY, P.
dc.date.accessioned2020-06-30T07:16:01Z
dc.date.available2020-06-30T07:16:01Z
dc.date.issued2019-01
dc.identifier.issn0022-202xen_US
dc.identifier.urihttps://oskar-bordeaux.fr/handle/20.500.12278/8315
dc.description.abstractEnThe Pemphigus Disease Area Index (PDAI) and Autoimmune Bullous Skin Disorder Intensity-Score (ABSIS) scores have been proposed to provide an objective measure of pemphigus activity. These scores have been evaluated only on already treated patients mainly with mild to moderate activity. The objective was to assess the interrater reliability of ABSIS and PDAI scores and their correlation with other severity markers in a large international study. Consecutive patients with newly diagnosed pemphigus were enrolled in 31 centers. Severity scores were recorded during a 24-month period by the same two blinded investigators. Serum was collected at each visit for ELISA measurement of anti-desmoglein antibodies. The intraclass correlation coefficient (ICC) and Spearman rank correlation coefficient were calculated. A total of 116 patients with pemphigus vulgaris (n = 84) or pemphigus foliaceus (n = 32) were included. At baseline, the ABSIS and PDAI ICCs were 0.90 (95% confidence interval [CI] = 0.85-0.93), and 0.91(95% CI = 0.87-0.94), respectively. The ICCs for PDAI were higher in moderate and extensive pemphigus (ICC = 0.82, 95% CI = 0.63-0.92 and ICC = 0.80, 95% CI = 0.62-0.90, respectively) than in patients with intermediate (significant) extent (ICC = 0.50, 95% CI = 0.27-0.68). Conversely, the ICCs for ABSIS were lower in patients with moderate extent (ICC = 0.44, 95% CI = 0.004-0.74) than in those with intermediate or extensive forms, (ICC = 0.69, 95% CI = 0.51-0.81 and ICC = 0.75, 95% CI = 0.51-0.88, respectively). During patients' follow-up, the ICCs of both ABSIS and PDAI scores remained higher than 0.70. ABSIS and PDAI skin (r = 0.71 and r = 0.75) but not mucosal (r = 0.32 and r = 0.37) subscores were correlated with the evolution of anti-DSG1 and anti-DSG3 ELISA values, respectively. ABSIS and PDAI scores are robust tools to accurately assess pemphigus activity.
dc.language.isoENen_US
dc.title.enLarge International Validation of ABSIS and PDAI Pemphigus Severity Scores
dc.title.alternativeJ Invest Dermatolen_US
dc.typeArticle de revueen_US
dc.identifier.doi10.1016/j.jid.2018.04.042en_US
dc.subject.halSciences du Vivant [q-bio]/Santé publique et épidémiologieen_US
dc.identifier.pubmed30301637en_US
bordeaux.journalThe Journal of investigative dermatologyen_US
bordeaux.page31-37en_US
bordeaux.volume139en_US
bordeaux.hal.laboratoriesBordeaux Population Health Research Center (BPH) - U1219en_US
bordeaux.issue1en_US
bordeaux.institutionUniversité de Bordeauxen_US
bordeaux.peerReviewedouien_US
bordeaux.inpressnonen_US
hal.exportfalse
bordeaux.COinSctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=The%20Journal%20of%20investigative%20dermatology&rft.date=2019-01&rft.volume=139&rft.issue=1&rft.spage=31-37&rft.epage=31-37&rft.eissn=0022-202x&rft.issn=0022-202x&rft.au=HEBERT,%20V.&BOULARD,%20C.&HOUIVET,%20Estelle&DUVERT%20LEHEMBRE,%20S.&BORRADORI,%20L.&rft.genre=article


Archivos en el ítem

ArchivosTamañoFormatoVer

No hay archivos asociados a este ítem.

Este ítem aparece en la(s) siguiente(s) colección(ones)

Mostrar el registro sencillo del ítem