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dc.rights.licenseopenen_US
hal.structure.identifierBordeaux population health [BPH]
dc.contributor.authorMALVY, Denis
dc.contributor.authorMCELROY, A. K.
dc.contributor.authorDE CLERCK, H.
dc.contributor.authorGUNTHER, S.
dc.contributor.authorVAN GRIENSVEN, J.
dc.date.accessioned2020-06-29T09:16:00Z
dc.date.available2020-06-29T09:16:00Z
dc.date.issued2019-03-02
dc.identifier.issn1474-547X (Electronic) 0140-6736 (Linking)en_US
dc.identifier.urihttps://oskar-bordeaux.fr/handle/20.500.12278/8259
dc.description.abstractEnEbolaviruses are pathogenic agents associated with a severe, potentially fatal, systemic disease in man and great apes. Four species of ebolaviruses have been identified in west or equatorial Africa. Once the more virulent forms enter the human population, transmission occurs primarily through contact with infected body fluids and can result in major epidemics in under-resourced settings. These viruses cause a disease characterised by systemic viral replication, immune suppression, abnormal inflammatory responses, major fluid and electrolyte losses, and high mortality. Despite recent progress on vaccines, and with no licensed prophylaxis or treatment available, case management is essentially supportive with management of severe multiple organ failure resulting from immune-mediated cell damage. The 2013-16 outbreak was classified by WHO as a Public Health Emergency of International Concern, which drew attention to the challenges of diseases caused by infections with ebolaviruses and questioned scientific, clinical, and societal preparation to handle future epidemics.
dc.language.isoENen_US
dc.subject.enIDLIC
dc.title.enEbola virus disease
dc.title.alternativeLanceten_US
dc.typeArticle de revueen_US
dc.identifier.doi10.1016/s0140-6736(18)33132-5en_US
dc.subject.halSciences du Vivant [q-bio]/Santé publique et épidémiologieen_US
dc.identifier.pubmed30777297en_US
bordeaux.journalThe Lanceten_US
bordeaux.page936-948en_US
bordeaux.volume393en_US
bordeaux.hal.laboratoriesBordeaux Population Health Research Center (BPH) - U1219en_US
bordeaux.issue10174en_US
bordeaux.institutionUniversité de Bordeauxen_US
bordeaux.peerReviewedouien_US
bordeaux.inpressnonen_US
hal.identifierhal-03209500
hal.version1
hal.date.transferred2021-04-27T09:32:44Z
hal.exporttrue
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