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Influence of activity space on the association between neighborhood characteristics and dementia risk: results from the 3-City study cohort

dc.rights.licenseopenen_US
dc.contributor.authorLETELLIER, N.
dc.contributor.authorCARRIERE, I.
dc.contributor.authorGUTIERREZ, L. A.
dc.contributor.authorGABELLE, A.
hal.structure.identifierBordeaux population health [BPH]
dc.contributor.authorDARTIGUES, Jean-Francois
ORCID: 0000-0001-9482-5529
IDREF: 058586105
hal.structure.identifierBordeaux population health [BPH]
dc.contributor.authorDUFOUIL, Carole
hal.structure.identifierBordeaux population health [BPH]
dc.contributor.authorHELMER, Catherine
dc.contributor.authorCADOT, E.
dc.contributor.authorBERR, C.
dc.date.accessioned2020-06-26T08:36:26Z
dc.date.available2020-06-26T08:36:26Z
dc.date.issued2019-01-07
dc.identifier.issn1471-2318en_US
dc.identifier.urihttps://oskar-bordeaux.fr/handle/20.500.12278/8213
dc.description.abstractEnBACKGROUND: Socioeconomic level of residential environment was found to influence cognitive performance. However, individuals from the same place of residence may be affected differently. We aim to investigate for the first time the influence of individual activity space on the association between neighborhood socioeconomic status (NSES) and the risk of dementia. METHODS: In the frame of the Three-City cohort, a French population-based study, we followed longitudinally (12 years) 7009 participants aged over 65. The activity space (i.e., the spatial area through which a person moves daily) was defined using two questions from Lawton's Instrumental Activities of Daily Living scale ("Goes shopping independently","Travels alone"), and one question about mobility restriction. The survival analysis was performed using a Cox marginal model that takes into account intra-neighborhood correlations and includes a large number of potential confounders. RESULTS: Among people with a limited activity space (n = 772, 11%), risk of dementia is increased in subjects living in a deprived area (characterized by high GINI index or low median income) compared to those living in more favored. CONCLUSION: This study shows that the individual activity space modifies the association between NSES and the risk of dementia providing a more complete picture of residential inequalities. If confirmed in different populations, these findings suggest that people with limited activity space and living in a deprived neighborhood are particularly at risk and should be targeted for prevention.
dc.language.isoENen_US
dc.rightsAttribution 3.0 United States
dc.rights.urihttps://creativecommons.org/licenses/by/3.0/us/
dc.subject.enLEHA
dc.subject.enSEPIA
dc.subject.enFR
dc.subject.enVINTAGE
dc.title.enInfluence of activity space on the association between neighborhood characteristics and dementia risk: results from the 3-City study cohort
dc.title.alternativeBMC Geriatren_US
dc.typeArticle de revueen_US
dc.identifier.doi10.1186/s12877-018-1017-7en_US
dc.subject.halSciences du Vivant [q-bio]/Santé publique et épidémiologieen_US
dc.identifier.pubmed30616586en_US
bordeaux.journalBMC geriatricsen_US
bordeaux.page4en_US
bordeaux.volume19en_US
bordeaux.hal.laboratoriesBordeaux Population Health Research Center (BPH) - U1219en_US
bordeaux.issue1en_US
bordeaux.institutionUniversité de Bordeauxen_US
bordeaux.teamLEHA_BPH
bordeaux.peerReviewedouien_US
bordeaux.inpressnonen_US
hal.exportfalse
bordeaux.COinSctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=BMC%20geriatrics&rft.date=2019-01-07&rft.volume=19&rft.issue=1&rft.spage=4&rft.epage=4&rft.eissn=1471-2318&rft.issn=1471-2318&rft.au=LETELLIER,%20N.&CARRIERE,%20I.&GUTIERREZ,%20L.%20A.&GABELLE,%20A.&DARTIGUES,%20Jean-Francois&rft.genre=article


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