Afficher la notice abrégée

Blood platelets and sepsis pathophysiology: A new therapeutic prospect in critical ill patients?

hal.structure.identifierBioingénierie tissulaire [BIOTIS]
hal.structure.identifierService Anesthésie - Réanimation [Bordeaux]
dc.contributor.authorDEWITTE, Antoine
hal.structure.identifierBioingénierie tissulaire [BIOTIS]
hal.structure.identifierCHU Bordeaux
dc.contributor.authorLEPREUX, Sébastien
hal.structure.identifierThe Barcelona Institute for Science and Technology [Barcelona, Spain]
dc.contributor.authorVILLENEUVE, Julien
hal.structure.identifierBioingénierie tissulaire [BIOTIS]
hal.structure.identifierCHU Bordeaux
dc.contributor.authorRIGOTHIER, Claire
hal.structure.identifierBioingénierie tissulaire [BIOTIS]
hal.structure.identifierCHU Bordeaux
dc.contributor.authorCOMBE, Christian
hal.structure.identifierService Anesthésie - Réanimation [Bordeaux]
hal.structure.identifierBiologie des maladies cardiovasculaires = Biology of Cardiovascular Diseases
dc.contributor.authorOUATTARA, Alexandre
hal.structure.identifierBioingénierie tissulaire [BIOTIS]
dc.contributor.authorRIPOCHE, Jean
dc.date.accessioned2021-06-10T07:04:41Z
dc.date.available2021-06-10T07:04:41Z
dc.date.issued2017-12
dc.identifier.issn2110-5820
dc.identifier.urihttps://oskar-bordeaux.fr/handle/20.500.12278/78991
dc.description.abstractEnBeyond haemostasis, platelets have emerged as versatile effectors of the immune response. The contribution of platelets in inflammation, tissue integrity and defence against infections has considerably widened the spectrum of their role in health and disease. Here, we propose a narrative review that first describes these new platelet attributes. We then examine their relevance to microcirculatory alterations in multi-organ dysfunction, a major sepsis complication. Rapid progresses that are made on the knowledge of novel platelet functions should improve the understanding of thrombocytopenia, a common condition and a predictor of adverse outcome in sepsis, and may provide potential avenues for management and therapy.
dc.language.isoen
dc.publisherSpringerOpen
dc.title.enBlood platelets and sepsis pathophysiology: A new therapeutic prospect in critical ill patients?
dc.typeArticle de revue
dc.identifier.doi10.1186/s13613-017-0337-7
dc.subject.halSciences du Vivant [q-bio]/Médecine humaine et pathologie/Cardiologie et système cardiovasculaire
bordeaux.journalAnnals of Intensive Care
bordeaux.page115
bordeaux.volume7
bordeaux.hal.laboratoriesBioingénierie Tissulaire (BioTis) - U1026*
bordeaux.issue1
bordeaux.institutionCNRS
bordeaux.institutionINSERM
bordeaux.institutionCHU de Bordeaux
bordeaux.institutionInstitut Bergonié
bordeaux.peerReviewedoui
hal.identifierinserm-02469457
hal.version1
hal.origin.linkhttps://hal.archives-ouvertes.fr//inserm-02469457v1
bordeaux.COinSctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=Annals%20of%20Intensive%20Care&rft.date=2017-12&rft.volume=7&rft.issue=1&rft.spage=115&rft.epage=115&rft.eissn=2110-5820&rft.issn=2110-5820&rft.au=DEWITTE,%20Antoine&LEPREUX,%20S%C3%A9bastien&VILLENEUVE,%20Julien&RIGOTHIER,%20Claire&COMBE,%20Christian&rft.genre=article


Fichier(s) constituant ce document

FichiersTailleFormatVue

Il n'y a pas de fichiers associés à ce document.

Ce document figure dans la(les) collection(s) suivante(s)

Afficher la notice abrégée