Afficher la notice abrégée

Effects of a physical activity programme to prevent physical performance decline in onco-geriatric patients: a randomized multicentre trial

dc.rights.licenseopenen_US
hal.structure.identifierCentre de résonance magnétique des systèmes biologiques [CRMSB]
dc.contributor.authorARRIETA, Haritz
dc.contributor.authorASTRUGUE, C.
dc.contributor.authorREGUEME, S.
dc.contributor.authorDURRIEU, J.
dc.contributor.authorMAILLARD, A.
dc.contributor.authorRIEGER, A.
dc.contributor.authorTERREBONNE, E.
dc.contributor.authorLAURENT, C.
dc.contributor.authorMAGET, B.
dc.contributor.authorSERVENT, V.
dc.contributor.authorLAVAU-DENES, S.
dc.contributor.authorDAUBA, J.
dc.contributor.authorFONCK, M.
hal.structure.identifierStatistics In System biology and Translational Medicine [SISTM]
hal.structure.identifierBordeaux population health [BPH]
dc.contributor.authorTHIEBAUT, Rodolphe
hal.structure.identifierCentre de résonance magnétique des systèmes biologiques [CRMSB]
dc.contributor.authorBOURDEL-MARCHASSON, Isabelle
dc.date.accessioned2020-05-07T09:18:24Z
dc.date.available2020-05-07T09:18:24Z
dc.date.issued2019
dc.identifier.issn2190-6009 (Electronic) 2190-5991 (Linking)en_US
dc.identifier.urihttps://oskar-bordeaux.fr/handle/20.500.12278/7502
dc.description.abstractEnBACKGROUND: Older adults with cancer experience negative long-term functional effects of both cancer and treatments. Exercise may minimize their age-related and cancer-related functional decline. METHODS: We conducted a multicentre open-label 12 month randomized clinical trial with two parallel arms including participants aged >/=70 years with lymphoma or carcinoma requiring curative treatment. The study started at the beginning of any phase of cancer treatment (surgery, chemotherapy, or radiotherapy). The usual care group (UCG) received the current national recommendations in physical activity (a guideline without specific counselling). The intervention group (IG) received 1 year phoned physical activity advice individually adapted to physical assessment (twice a month during the first 6 months and then monthly). The primary outcome was the proportion of subjects with a 1 year decreased short physical performance battery (SPPB) score of 1 point or more. Physical, cognitive, and clinical secondary outcomes were also investigated. RESULTS: We allocated 301 participants (age 76.7 +/- 5.0, female 60.6%) to each group. At baseline, the median SPPB was 10/12 in both groups. Breast was the most frequent tumour site (35.7%). After 1 year, 14.0% of participants in the UCG and 18.7% in the IG had a decrease in SPPB score of 1 point or more (P = 0.772). At 2 years, there was no difference in SPPB, gait speed, International Physical Activity Questionnaire score, and verbal fluency. Subgroup analyses after 2 years showed a decline in SPPB for 29.8% of UCG and 5.0% of IG breast cancer participants (P = 0.006), in 21.7% of UCG and 6.2% of IG female participants (P = 0.019), and in 24.5% of UCG and 11.1% of IG normal nutritional status participants (P = 0.009). Falls, hospitalization, institutionalization, and death rates were similar in both groups. CONCLUSIONS: Personalized phoned physical activity advice had not reduced functional decline at 1 year but provided preliminary evidence that may prevent physical performance decline at 2 years in older adults with breast cancer.
dc.language.isoENen_US
dc.rightsAttribution-NonCommercial 3.0 United States
dc.rights.urihttps://creativecommons.org/licenses/by-nc/3.0/us/
dc.subject.enSISTM
dc.subject.enUSMR
dc.title.enEffects of a physical activity programme to prevent physical performance decline in onco-geriatric patients: a randomized multicentre trial
dc.title.alternativeJ Cachexia Sarcopenia Muscleen_US
dc.typeArticle de revueen_US
dc.identifier.doi10.1002/jcsm.12382en_US
dc.subject.halSciences du Vivant [q-bio]/Santé publique et épidémiologieen_US
dc.identifier.pubmed30829460en_US
bordeaux.journalJournal of Cachexia, Sarcopenia and Muscleen_US
bordeaux.page287-297en_US
bordeaux.volume10en_US
bordeaux.hal.laboratoriesBordeaux Population Health Research Center (BPH) - U1219en_US
bordeaux.issue2en_US
bordeaux.institutionUniversité de Bordeauxen_US
bordeaux.teamSISTM_BPH
bordeaux.peerReviewedouien_US
bordeaux.inpressnonen_US
hal.identifierhal-03160734
hal.version1
hal.date.transferred2021-03-05T13:36:55Z
hal.exporttrue
bordeaux.COinSctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=Journal%20of%20Cachexia,%20Sarcopenia%20and%20Muscle&rft.date=2019&rft.volume=10&rft.issue=2&rft.spage=287-297&rft.epage=287-297&rft.eissn=2190-6009%20(Electronic)%202190-5991%20(Linking)&rft.issn=2190-6009%20(Electronic)%202190-5991%20(Linking)&rft.au=ARRIETA,%20Haritz&ASTRUGUE,%20C.&REGUEME,%20S.&DURRIEU,%20J.&MAILLARD,%20A.&rft.genre=article


Fichier(s) constituant ce document

Thumbnail
Nom:
BPH_JCSM_2019_Arrieta.pdf
Taille:
287.4Ko
Format:
PDF
Voir/Ouvrir

Ce document figure dans la(les) collection(s) suivante(s)

Afficher la notice abrégée