REM1.3's phospho-status defines its plasma membrane nanodomain organization and activity in restricting PVX cell-to-cell movement
| dc.rights.license | open | en_US |
| hal.structure.identifier | Laboratoire de biogenèse membranaire [LBM] | |
| dc.contributor.author | PERRAKI, A. | |
| hal.structure.identifier | Laboratoire de biogenèse membranaire [LBM] | |
| dc.contributor.author | GRONNIER, J. | |
| hal.structure.identifier | Laboratoire de biogenèse membranaire [LBM] | |
| dc.contributor.author | GOUGUET, P. | |
| hal.structure.identifier | Biologie du fruit et pathologie [BFP] | |
| dc.contributor.author | BOUDSOCQ, M. | |
| hal.structure.identifier | Laboratoire de biogenèse membranaire [LBM] | |
| dc.contributor.author | DEROUBAIX, A. F. | |
| hal.structure.identifier | Biologie du fruit et pathologie [BFP] | |
| dc.contributor.author | SIMON, V. | |
| hal.structure.identifier | Biologie du fruit et pathologie [BFP] | |
| dc.contributor.author | GERMAN-RETANA, S. | |
| hal.structure.identifier | Laboratoire de biogenèse membranaire [LBM] | |
| hal.structure.identifier | Chimie et Biologie des Membranes et des Nanoobjets [CBMN] | |
| dc.contributor.author | LEGRAND, A. | |
| hal.structure.identifier | Chimie et Biologie des Membranes et des Nanoobjets [CBMN] | |
| dc.contributor.author | HABENSTEIN, Birgit | |
| dc.contributor.author | ZIPFEL, C. | |
| hal.structure.identifier | Laboratoire de biogenèse membranaire [LBM] | |
| dc.contributor.author | BAYER, Emmanuelle | |
| hal.structure.identifier | Laboratoire de biogenèse membranaire [LBM] | |
| dc.contributor.author | MONGRAND, Sébastien | |
| hal.structure.identifier | Laboratoire de biogenèse membranaire [LBM] | |
| dc.contributor.author | GERMAIN, Veronique | |
| dc.date.accessioned | 2020-04-06T13:57:39Z | |
| dc.date.available | 2020-04-06T13:57:39Z | |
| dc.date.issued | 2018 | |
| dc.identifier.issn | 1553-7366 | en_US |
| dc.identifier.other | (https://www.arabidopsis.org/index.jsp), and GenBank/EMBL (https://www.ncbi.nlm.nih.gov/genbank/) databases under the accession numbers: StREM1.3 (NP_001274989), AtREM1.2 (At3g61260), AtREM1.3 (At2g45820), AtCPK3 (At4g23650). | en_US |
| dc.identifier.uri | https://oskar-bordeaux.fr/handle/20.500.12278/4120 | |
| dc.description.abstractEn | Plants respond to pathogens through dynamic regulation of plasma membrane-bound signaling pathways. To date, how the plant plasma membrane is involved in responses to viruses is mostly unknown. Here, we show that plant cells sense the Potato virus X (PVX) COAT PROTEIN and TRIPLE GENE BLOCK 1 proteins and subsequently trigger the activation of a membrane-bound calcium-dependent kinase. We show that the Arabidopsis thaliana CALCIUM-DEPENDENT PROTEIN KINASE 3-interacts with group 1 REMORINs in vivo, phosphorylates the intrinsically disordered N-terminal domain of the Group 1 REMORIN REM1.3, and restricts PVX cell-to-cell movement. REM1.3's phospho-status defines its plasma membrane nanodomain organization and is crucial for REM1.3-dependent restriction of PVX cell-to-cell movement by regulation of callose deposition at plasmodesmata. This study unveils plasma membrane nanodomain-associated molecular events underlying the plant immune response to viruses. | |
| dc.description.sponsorship | Facteurs cellulaires recrutés par les potyvirus pour leur transport intercellulaire : de nouvelles sources de résistance des plantes? - ANR-16-CE20-0008 | en_US |
| dc.language.iso | EN | en_US |
| dc.subject.en | Phosphorylation | |
| dc.subject.en | Leaves | |
| dc.subject.en | In vitro kinase assay | |
| dc.subject.en | Arabidopsis thaliana | |
| dc.subject.en | Protein extraction | |
| dc.subject.en | Membrane proteins; Cell membranes | |
| dc.subject.en | Agrobacterium tumefaciens | |
| dc.title.en | REM1.3's phospho-status defines its plasma membrane nanodomain organization and activity in restricting PVX cell-to-cell movement | |
| dc.type | Article de revue | en_US |
| dc.identifier.doi | 10.1371/journal.ppat.1007378 | |
| dc.subject.hal | Chimie/Matériaux | en_US |
| dc.description.sponsorshipEurope | Signaling initiation and specificity in BAK1-dependent receptor kinase-mediated innate immunity in Arabidopsis | en_US |
| bordeaux.journal | Plos Pathogens | en_US |
| bordeaux.volume | 14 | en_US |
| bordeaux.hal.laboratories | Institut de Chimie & de Biologie des Membranes & des Nano-objets (CBMN) - UMR 5248 | |
| bordeaux.issue | 11 | en_US |
| bordeaux.institution | Bordeaux INP | en_US |
| bordeaux.institution | Université de Bordeaux | en_US |
| bordeaux.peerReviewed | oui | en_US |
| bordeaux.inpress | non | en_US |
| hal.identifier | hal-03184358 | |
| hal.version | 1 | |
| hal.date.transferred | 2021-03-29T11:58:58Z | |
| hal.export | true | |
| bordeaux.COinS | ctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=Plos%20Pathogens&rft.date=2018&rft.volume=14&rft.issue=11&rft.eissn=1553-7366&rft.issn=1553-7366&rft.au=PERRAKI,%20A.&GRONNIER,%20J.&GOUGUET,%20P.&BOUDSOCQ,%20M.&DEROUBAIX,%20A.%20F.&rft.genre=article |
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