Background Better knowledge of wine composition, especially that of anthocyanin-derived pigments, has helped improve wine quality over the years. The use of micro-oxygenation (MOX), which consists in adding low quantities of oxygen at different stages of the winemaking process, contributes to enhancing and stabilizing wine color through the formation of stable pigments called pyranoanthocyanins, while the cycloaddition of anthocyanins requires an oxidation step. Scope and approach This review describes the formation kinetics and the evolution of the concentrations of the various groups of pyranoanthocyanins. Both non-oxygenated and oxygenated varietal red wine samples are compared in order to determine the impact of MOX on pyranoanthocyanin contents. Key findings and conclusions During alcoholic fermentation, the concentration of vitisin A increases due to the availability of pyruvic acid and progressively decreases with aging. Higher contents are found in Port red wines. MOX can enhance the concentrations in dry red wines but the contents remain lower than those found in Port wines. The formation of vitisin B can be promoted by the oxidation of ethanol in acetaldehyde but the results depend on the varietal red wine used. Flavanol-pyranoanthocyanin contents also vary according to wine age, with a reported decreasing concentration during aging for Port and dry red wines. After MOX treatment, their concentrations increase with a more acidic pH and a higher oxygen rate. The increase of the content in pyranoanthocyanins after two years of ageing contributes to stabilize wine colour. Further studies will determine the impact of oxygen on phenyl-pyranoanthocyanins since data are still scarce on the subject.Read less <