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Suitability of infrared spectroscopy for drug checking in harm reduction centres

dc.rights.licenseopenen_US
hal.structure.identifierBordeaux population health [BPH]
dc.contributor.authorGONCALVES, Ruben
dc.contributor.authorTITIER, K.
dc.contributor.authorLATOUR, V.
dc.contributor.authorPEYRE, A.
dc.contributor.authorCASTAING, N.
hal.structure.identifierBordeaux population health [BPH]
dc.contributor.authorDAVELUY, Amelie
hal.structure.identifierBordeaux population health [BPH]
dc.contributor.authorMOLIMARD, Mathieu
dc.date.accessioned2021-03-15T13:42:42Z
dc.date.available2021-03-15T13:42:42Z
dc.date.issued2020-11-15
dc.identifier.issn1873-4758 (Electronic) 0955-3959 (Linking)en_US
dc.identifier.urihttps://oskar-bordeaux.fr/handle/20.500.12278/26663
dc.description.abstractEnDrug checking is a service for people who use drugs that includes product analysis and an individual interview including results feedback and harm reduction counselling. It uses different analytical methods but few studies demonstrate their value in current practice. The main objective of this work is to compare the analytical performance of IR spectroscopy to laboratory reference method in the context of drug checking in a harm reduction centre. The secondary objectives are to carry out a description of the people who use drugs requesting a product analysis, and to compare the assumed compositions of products purchased with their real compositions. During 2018, all requests for drug testing analysis were included for on-site analysis by IR spectrometry in a harm reduction center and verified by the reference method (UPLC-HRMS) at Bordeaux University Hospital Center. Socioeconomic and product data were also collected. One hundred and thirty-six samples were collected. The results obtained with IR and UPLC-HRMS were compared. IR spectrometry results did not match with reference method in 8 % (n=11) of cases, corresponding to blotters, cannabis and some psychoactive substances present in mixture or in small quantities. Among the products collected, only 5.1 % (n=7) did not correspond to the declared product, either alone or with adulterants. The IR spectrometer allows a simple and rapid detection of at least one molecule, most often the one of interest. However, it is limited to powder and tablet type matrices and is not suitable for blotters, cannabis, mixed or low content substances for which high resolution mass spectrometry remains the reference method. � 2020 Elsevier B.V.
dc.language.isoENen_US
dc.title.enSuitability of infrared spectroscopy for drug checking in harm reduction centres
dc.title.alternativeInt J Drug Policyen_US
dc.typeArticle de revueen_US
dc.identifier.doi10.1016/j.drugpo.2020.103037en_US
dc.subject.halSciences du Vivant [q-bio]/Santé publique et épidémiologieen_US
dc.identifier.pubmed33207305en_US
bordeaux.journalInternational Journal of Drug Policyen_US
bordeaux.volume88en_US
bordeaux.hal.laboratoriesBordeaux Population Health Research Center (BPH) - U1219en_US
bordeaux.institutionUniversité de Bordeauxen_US
bordeaux.teamPharmacoEpi-Drugsen_US
bordeaux.peerReviewedouien_US
bordeaux.inpressnonen_US
hal.identifierhal-03169608
hal.version1
hal.date.transferred2021-03-15T13:42:46Z
hal.exporttrue
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