Why Methodology Is Important: Coffee as a Candidate Treatment for COVID-19?
| dc.rights.license | open | en_US |
| hal.structure.identifier | Bordeaux population health [BPH] | |
| dc.contributor.author | BELAROUSSI, Yaniss | |
| hal.structure.identifier | Bordeaux population health [BPH] | |
| dc.contributor.author | ROBLOT, Paul | |
| dc.contributor.author | PEIFFER-SMADJA, N. | |
| dc.contributor.author | DELAYE, T. | |
| hal.structure.identifier | Bordeaux population health [BPH] | |
| dc.contributor.author | MATHOULIN-PELISSIER, Simone | |
| hal.structure.identifier | Bordeaux population health [BPH] | |
| dc.contributor.author | LEMEUX, Joffrey | |
| dc.contributor.author | LE MOAL, G. | |
| dc.contributor.author | CAUMES, E. | |
| dc.contributor.author | ROBLOT, F. | |
| dc.contributor.author | BLEIBTREU, A. | |
| dc.date.accessioned | 2021-03-03T15:50:06Z | |
| dc.date.available | 2021-03-03T15:50:06Z | |
| dc.date.issued | 2020-11-17 | |
| dc.identifier.issn | 2077-0383 (Print) | en_US |
| dc.identifier.uri | https://oskar-bordeaux.fr/handle/20.500.12278/26411 | |
| dc.description.abstractEn | BACKGROUND: During this pandemic situation, some studies have led to hasty conclusions about Corona Virus Disease-19 (COVID-19) treatment, due to a lack of methodology. This pedagogic study aimed to highlight potential biases in research on COVID-19 treatment. METHODS: We evaluate the effect of coffee's active part, 1,3,7-trimethylxanthine (TMX) on patients with COVID-19. A cohort of 93 patients, with a diagnosis of COVID-19 is analyzed. RESULTS: TMX group and control group included, respectively, 26 and 67 patients. In the TMX group, patients had a median length of stay in hospital of 5.5 days shorter than in the control group (9.5 vs. 15 days, p < 0.05). Patients in the control group were more severe than patients in the TMX group with a significantly higher National Early Warning Score 2 (NEWS-2 score) (8 vs. 6, p = 0.002). CONCLUSIONS: Multiple biases prevents us from concluding to an effect of coffee on COVID-19. Despite an important social pressure during this crisis, methodology and conscientiousness are the best way to avoid hasty conclusions that can be deleterious for patients. Identifier: NCT04395742. | |
| dc.language.iso | EN | en_US |
| dc.rights | Attribution 3.0 United States | * |
| dc.rights.uri | http://creativecommons.org/licenses/by/3.0/us/ | * |
| dc.title.en | Why Methodology Is Important: Coffee as a Candidate Treatment for COVID-19? | |
| dc.title.alternative | J Clin Med | en_US |
| dc.type | Article de revue | en_US |
| dc.identifier.doi | 10.3390/jcm9113691 | en_US |
| dc.subject.hal | Sciences du Vivant [q-bio]/Santé publique et épidémiologie | en_US |
| dc.identifier.pubmed | 33213035 | en_US |
| bordeaux.journal | Journal of Clinical Medicine | en_US |
| bordeaux.volume | 9 | en_US |
| bordeaux.hal.laboratories | Bordeaux Population Health Research Center (BPH) - U1219 | en_US |
| bordeaux.issue | 11 | en_US |
| bordeaux.institution | Université de Bordeaux | en_US |
| bordeaux.team | EPICENE_BPH | |
| bordeaux.peerReviewed | oui | en_US |
| bordeaux.inpress | non | en_US |
| hal.export | false | |
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