Regression analysis in an illness-death model with interval-censored data: A pseudo-value approach
dc.rights.license | open | en_US |
hal.structure.identifier | Bordeaux population health [BPH] | |
dc.contributor.author | SABATHE, Camille | |
dc.contributor.author | ANDERSEN, P. K. | |
hal.structure.identifier | Bordeaux population health [BPH] | |
dc.contributor.author | HELMER, Catherine | |
dc.contributor.author | GERDS, T. A. | |
hal.structure.identifier | Bordeaux population health [BPH] | |
dc.contributor.author | JACQMIN-GADDA, Helene | |
hal.structure.identifier | Bordeaux population health [BPH] | |
dc.contributor.author | JOLY, Pierre | |
dc.date.accessioned | 2021-02-16T13:29:44Z | |
dc.date.available | 2021-02-16T13:29:44Z | |
dc.date.issued | 2020 | |
dc.identifier.issn | 1477-0334 (Electronic) 0962-2802 (Linking) | en_US |
dc.identifier.uri | https://oskar-bordeaux.fr/handle/20.500.12278/26252 | |
dc.description.abstractEn | Pseudo-values provide a method to perform regression analysis for complex quantities with right-censored data. A further complication, interval-censored data, appears when events such as dementia are studied in an epidemiological cohort. We propose an extension of the pseudo-value approach for interval-censored data based on a semi-parametric estimator computed using penalised likelihood and splines. This estimator takes interval-censoring and competing risks into account in an illness-death model. We apply the pseudo-value approach to three mean value parameters of interest in studies of dementia: the probability of staying alive and non-demented, the restricted mean survival time without dementia and the absolute risk of dementia. Simulation studies are conducted to examine properties of pseudo-values based on this semi-parametric estimator. The method is applied to the French cohort PAQUID, which included more than 3,000 non-demented subjects, followed for dementia for more than 25 years. | |
dc.language.iso | EN | en_US |
dc.subject | LEHA | |
dc.subject | Biostatistics | |
dc.title.en | Regression analysis in an illness-death model with interval-censored data: A pseudo-value approach | |
dc.title.alternative | Stat Methods Med Res | en_US |
dc.type | Article de revue | en_US |
dc.identifier.doi | 10.1177/0962280219842271 | en_US |
dc.subject.hal | Sciences du Vivant [q-bio]/Santé publique et épidémiologie | en_US |
dc.identifier.pubmed | 30991888 | en_US |
bordeaux.journal | Statistical Methods in Medical Research | en_US |
bordeaux.page | 752-764 | en_US |
bordeaux.volume | 29 | en_US |
bordeaux.hal.laboratories | Bordeaux Population Health Research Center (BPH) - U1219 | en_US |
bordeaux.issue | 3 | en_US |
bordeaux.institution | Université de Bordeaux | en_US |
bordeaux.team | BIOSTAT_BPH | en_US |
bordeaux.team | LEHA_BPH | |
bordeaux.peerReviewed | oui | en_US |
bordeaux.inpress | non | en_US |
hal.identifier | hal-03142996 | |
hal.version | 1 | |
hal.date.transferred | 2021-02-16T13:29:48Z | |
hal.export | true | |
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