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dc.rights.licenseopenen_US
hal.structure.identifierBordeaux population health [BPH]
dc.contributor.authorDELYFER, Marie-Noelle
hal.structure.identifierBordeaux population health [BPH]
dc.contributor.authorLEGOUT, Pierre
hal.structure.identifierBordeaux population health [BPH]
dc.contributor.authorLE GOFF, Melanie
ORCID: 0000-0003-2848-6287
dc.contributor.authorBLAIZEAU, M.
hal.structure.identifierBordeaux population health [BPH]
dc.contributor.authorROUGIER, Marie-Benedicte
hal.structure.identifierBordeaux population health [BPH]
dc.contributor.authorSCHWEITZER, Cedric
ORCID: 0000-0002-2162-9479
IDREF: 133631583
hal.structure.identifierBordeaux population health [BPH]
dc.contributor.authorKOROBELNIK, Jean-Francois
ORCID: 0000-0002-4438-9535
IDREF: 028739272
hal.structure.identifierBordeaux population health [BPH]
dc.contributor.authorDELCOURT, Cecile
ORCID: 0000-0002-2099-0481
IDREF: 035105291
dc.date.accessioned2021-01-21T10:34:46Z
dc.date.available2021-01-21T10:34:46Z
dc.date.issued2020
dc.identifier.issn1755-3768 (Electronic) 1755-375X (Linking)en_US
dc.identifier.urihttps://oskar-bordeaux.fr/handle/20.500.12278/25939
dc.description.abstractEnPurpose To analyse and compare the prevalence of epiretinal membranes (ERMs) obtained using either standard retinal colour images or spectral‐domain optical coherence tomography (SD‐OCT) in a population‐based setting of French elderly subjects. Methods Six hundred twenty‐four subjects of the Alienor cohort aged 75 years or older underwent both colour fundus imaging and SD‐OCT examinations. The ERMs were graded from retinal images and SD‐OCT macular scans in a masked fashion. On SD‐OCT images, the early ERMs, mature contractile ERMs without foveal modifications and mature contractile ERMs with foveal alterations were distinguished. Results 610 (97.8%) subjects had gradable SD‐OCT examinations, and 511 (81.9%) had gradable fundus images in at least one eye. According to colour photographs, 11.6% of participants had definite ERMs. From SD‐OCT images, 52.8% of the subjects had early ERMs, 7.4% had mature ERMs without foveal involvement, and 9.7% had mature ERMs with foveal alterations. Regardless of the imaging method used, the ERMs were more often observed in pseudophakic eyes than in phakic eyes. Comparison of ERM assessment using fundus photographs versus SD‐OCT images demonstrated that the specificity of retinal colour images was good (>89.3%), whereas the sensitivity remained low even though it increased with ERM severity on SD‐OCT images. Conclusions Spectral‐domain optical coherence tomography (SD‐OCT) examinations have high feasibility in this elderly population and are much more sensitive than standard colour images for ERM assessments, especially in the early stages of the disease. Our results further highlight the need to use SD‐OCT instead of colour retinal photographs for the classification of ERMs in epidemiological studies.
dc.language.isoENen_US
dc.subjectLEHA
dc.title.enPrevalence of epiretinal membranes in the ageing population using retinal colour images and SD-OCT: the Alienor Study
dc.title.alternativeActa Ophthalmolen_US
dc.typeArticle de revueen_US
dc.identifier.doi10.1111/aos.14422en_US
dc.subject.halSciences du Vivant [q-bio]/Santé publique et épidémiologieen_US
dc.identifier.pubmed32304162en_US
bordeaux.journalActa Ophtalmologicaen_US
bordeaux.pagee830-e838en_US
bordeaux.volume98en_US
bordeaux.hal.laboratoriesBordeaux Population Health Research Center (BPH) - U1219en_US
bordeaux.issue7en_US
bordeaux.institutionUniversité de Bordeauxen_US
bordeaux.teamLEHA_BPH
bordeaux.peerReviewedouien_US
bordeaux.inpressnonen_US
hal.identifierhal-03117498
hal.version1
hal.date.transferred2021-01-21T10:34:50Z
hal.exporttrue
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