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Prevalence of hypercholesterolemia in Nigeria: a systematic review and meta-analysis

dc.rights.licenseopenen_US
dc.contributor.authorADELOYE, D.
dc.contributor.authorABAA, D. Q.
dc.contributor.authorOWOLABI, E. O.
hal.structure.identifierBordeaux population health [BPH]
dc.contributor.authorALE, Boni Maxime
dc.contributor.authorMPAZANJE, R. G.
dc.contributor.authorDEWAN, M. T.
dc.contributor.authorOMOYELE, C.
dc.contributor.authorEZEIGWE, N.
dc.contributor.authorALEMU, W.
dc.contributor.authorHARHAY, M. O.
dc.contributor.authorAUTA, A.
dc.contributor.authorADEWOLE, I. F.
dc.date.accessioned2021-01-12T14:30:58Z
dc.date.available2021-01-12T14:30:58Z
dc.date.issued2020
dc.identifier.issn0033-3506en_US
dc.identifier.urihttps://oskar-bordeaux.fr/handle/20.500.12278/23760
dc.description.abstractEnABSTRACT Objectives: Elevated blood cholesterol (hypercholesterolemia) is a significant cause of cardiovascular disease. We aimed to estimate national and zonal prevalence of hypercholesterolemia in Nigeria to help guide targeted public health programs. Design: This is a systematic review and synthesis of publicly available epidemiologic data on hypercholesterolemia in Nigeria. Methods: We systematically searched MEDLINE, EMBASE, Global Health, and Africa Journals Online for studies on the prevalence of hypercholesterolemia in Nigeria published between 1990 and 2018. We used a random-effects meta-analysis (Freeman-Tukey double arscine transformation) and meta-regression model to estimate the prevalence of hypercholesterolemia in Nigeria in 1995 and 2015. Results: 13 studies (n=16981) were retrieved. The pooled crude prevalence of hypercholesterolemia in Nigeria was 38% (95% CI: 26-51), with prevalence in women slightly higher (42%, 23-63) compared to men at (38%, 20-58). The prevalence was highest in the South-south (53%, 38-68) and lowest in the South-west (3%, 2-4) and North-east (4%, 2-7). Urban dwellers had a significantly higher rate (52%, 24-79) compared to rural dwellers (10%, 6-15). We estimated over 8.2 million persons (age-adjusted prevalence 16.5%) aged 20 years or more had hypercholesterolemia in Nigeria in 1995, increasing to 21.9 million persons (age-adjusted prevalence 25.9%) in 2015. Conclusions: Our findings suggest a high prevalence of hypercholesterolemia in Nigeria. Urbanization, lifestyles, diets, and culture appear to be driving an increasing prevalence, especially among women. Population-wide awareness and education on reducing elevated cholesterol levels and associated risks should be prioritised.
dc.language.isoENen_US
dc.title.enPrevalence of hypercholesterolemia in Nigeria: a systematic review and meta-analysis
dc.title.alternativePublic Healthen_US
dc.typeArticle de revueen_US
dc.identifier.doi10.1016/j.puhe.2019.09.002en_US
dc.subject.halSciences du Vivant [q-bio]/Santé publique et épidémiologieen_US
bordeaux.journalPublic healthen_US
bordeaux.page167-178en_US
bordeaux.volume178en_US
bordeaux.hal.laboratoriesBordeaux Population Health Research Center (BPH) - U1219en_US
bordeaux.institutionUniversité de Bordeauxen_US
bordeaux.peerReviewedouien_US
bordeaux.inpressnonen_US
hal.identifierhal-03107406
hal.version1
hal.date.transferred2021-01-12T14:31:03Z
hal.exporttrue
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