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The effects of periodontal treatment on diabetic patients: The DIAPERIO randomized controlled trial

dc.rights.licenseopenen_US
dc.contributor.authorVERGNES, J. N.
dc.contributor.authorCANCEILL, T.
dc.contributor.authorVINEL, A.
dc.contributor.authorLAURENCIN-DALICIEUX, S.
dc.contributor.authorMAUPAS-SCHWALM, F.
dc.contributor.authorBLASCO-BAQUE, V.
dc.contributor.authorHANAIRE, H.
hal.structure.identifierBordeaux population health [BPH]
dc.contributor.authorARRIVE, Elise
hal.structure.identifierBordeaux population health [BPH]
dc.contributor.authorRIGALLEAU, Vincent
dc.contributor.authorNABET, C.
dc.contributor.authorSIXOU, M.
dc.contributor.authorGOURDY, P.
dc.contributor.authorMONSARRAT, P.
dc.date.accessioned2021-01-06T12:27:27Z
dc.date.available2021-01-06T12:27:27Z
dc.date.issued2018-10
dc.identifier.issn1600-051X (Electronic) 0303-6979 (Linking)en_US
dc.identifier.urihttps://oskar-bordeaux.fr/handle/20.500.12278/23704
dc.description.abstractEnAIM: To assess whether periodontal treatment can lead to clinical, glycaemic control and quality of life improvements in metabolically unbalanced diabetic patients (type 1 or type 2) diagnosed with periodontitis. METHODS: In this open-labelled randomized controlled trial, diabetic subjects (n = 91) were given "immediate" or "delayed" periodontal treatment (full-mouth non-surgical scaling and root planing, systemic antibiotics, and oral health instructions). The main outcome was the effect on glycated haemoglobin (HbA1C ) and fructosamine levels. The General Oral Health Assessment Index and the SF-36 index were used to assess quality of life (QoL). RESULTS: Periodontal health significantly improved after periodontal treatment (p < 0.001). Periodontal treatment seemed to be safe but had no significant effects on glycaemic control based on HbA1C (adjusted mean difference with a 95% confidence interval (aMD) of 0.04 [-0.16;0.24]) and fructosamine levels (aMD 5.0 [-10.2;20.2]). There was no obvious evidence of improvement in general QoL after periodontal treatment. However, there was significant improvement in oral health-related QoL (aMD 7.0 [2.4;11.6], p = 0.003). CONCLUSION: Although periodontal treatment showed no clinical effect on glycaemic control in this trial, important data were provided to support periodontal care among diabetic patients. Periodontal treatment is safe and improves oral health-related QoL in patients living with diabetes. ISRCTN15334496.
dc.language.isoENen_US
dc.subject.enIDLIC
dc.subject.enLEHA
dc.title.enThe effects of periodontal treatment on diabetic patients: The DIAPERIO randomized controlled trial
dc.title.alternativeJ Clin Periodontolen_US
dc.typeArticle de revueen_US
dc.identifier.doi10.1111/jcpe.13003en_US
dc.subject.halSciences du Vivant [q-bio]/Santé publique et épidémiologieen_US
dc.identifier.pubmed30136741en_US
bordeaux.journalJournal of Clinical Periodontologyen_US
bordeaux.page1150-1163en_US
bordeaux.volume45en_US
bordeaux.hal.laboratoriesBordeaux Population Health Research Center (BPH) - U1219en_US
bordeaux.issue10en_US
bordeaux.institutionUniversité de Bordeauxen_US
bordeaux.teamIDLICen_US
bordeaux.teamLEHA_BPH
bordeaux.peerReviewedouien_US
bordeaux.inpressnonen_US
hal.identifierhal-03099911
hal.version1
hal.date.transferred2021-01-06T12:27:31Z
hal.exporttrue
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