Thermoinduced Crystallization-Driven Self-Assembly of Bioinspired Block Copolymers in Aqueous Solution.
| dc.rights.license | embargo | en_US |
| hal.structure.identifier | Qingdao University of Science and Technology | |
| dc.contributor.author | WANG, Zhiwei | |
| hal.structure.identifier | Qingdao University of Science and Technology | |
| dc.contributor.author | LIN, Min | |
| hal.structure.identifier | Laboratoire de Chimie des Polymères Organiques [LCPO] | |
| hal.structure.identifier | Team 3 LCPO : Polymer Self-Assembly & Life Sciences | |
| dc.contributor.author | BONDUELLE, Colin
IDREF: 134527046 | |
| hal.structure.identifier | Qingdao University of Science and Technology | |
| dc.contributor.author | LI, Rongye | |
| hal.structure.identifier | Qingdao University of Science and Technology | |
| dc.contributor.author | SHI, Zhekun | |
| hal.structure.identifier | Lawrence Berkeley National Laboratory [Berkeley] [LBNL] | |
| dc.contributor.author | ZHU, Chenhui | |
| hal.structure.identifier | Laboratoire de Chimie des Polymères Organiques [LCPO] | |
| hal.structure.identifier | Team 3 LCPO : Polymer Self-Assembly & Life Sciences | |
| dc.contributor.author | LECOMMANDOUX, Sebastien | |
| hal.structure.identifier | Qingdao University of Science and Technology | |
| dc.contributor.author | LI, Zhibo | |
| hal.structure.identifier | Qingdao University of Science and Technology | |
| dc.contributor.author | SUN, Jing | |
| dc.date.accessioned | 2020-12-24T10:13:21Z | |
| dc.date.available | 2020-12-24T10:13:21Z | |
| dc.date.issued | 2020-07-28 | |
| dc.identifier.issn | 1526-4602 | en_US |
| dc.identifier.uri | https://oskar-bordeaux.fr/handle/20.500.12278/23598 | |
| dc.description.abstractEn | Delicate control over architectures via crystallization-driven self-assembly (CDSA) in aqueous solution, particularly combined with external stimuli, is rare and challenging. Here, we report a stepwise CDSA process thermally initiated from amphiphilic poly(-allylglycine)-poly(-octylglycine) (PNAG--PNOG) conjugated with thiol-terminated triethylene glycol monomethyl ethers ((PNAG--EG)--PNOG) in aqueous solution. The diblock copolymers show a reversible thermoresponsive behavior with nearly identical cloud points in both heating and cooling runs. In contrast, the morphology transition of the assemblies is irreversible upon a heating-cooling cycle because of the presence of a confined domain arising from crystalline PNOG, which allows for the achievement of different nanostructured assemblies by the same polymer. We demonstrated that the thermoresponsive property of PNAG--EG initiates assembly kinetically that is subsequently promoted by crystallization of PNOG thermodynamically. The irreversible morphology transition behavior provides a convenient platform for comparing the cellular uptake efficiency of nanostructured assemblies with various morphologies that are otherwise similar. | |
| dc.language.iso | EN | en_US |
| dc.rights | Attribution-NonCommercial-NoDerivs 3.0 United States | * |
| dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/3.0/us/ | * |
| dc.subject.en | Morphology | |
| dc.subject.en | Crystallization | |
| dc.subject.en | Solution chemistry | |
| dc.subject.en | Copolymers | |
| dc.subject.en | Transmission electron microscopy | |
| dc.title.en | Thermoinduced Crystallization-Driven Self-Assembly of Bioinspired Block Copolymers in Aqueous Solution. | |
| dc.title.alternative | Biomacromolecules | en_US |
| dc.type | Article de revue | en_US |
| dc.identifier.doi | 10.1021/acs.biomac.0c00844 | en_US |
| dc.identifier.pubmed | 32786675 | en_US |
| bordeaux.journal | Biomacromolecules | en_US |
| bordeaux.page | 3411-3419 | en_US |
| bordeaux.volume | 21 | en_US |
| bordeaux.hal.laboratories | Laboratoire de Chimie des Polymères Organiques (LCPO) - UMR 5629 | en_US |
| bordeaux.issue | 8 | en_US |
| bordeaux.institution | Bordeaux INP | en_US |
| bordeaux.institution | Université de Bordeaux | en_US |
| bordeaux.peerReviewed | oui | en_US |
| bordeaux.inpress | non | en_US |
| bordeaux.import.source | pubmed | |
| hal.export | false | |
| workflow.import.source | pubmed | |
| bordeaux.COinS | ctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=Biomacromolecules&rft.date=2020-07-28&rft.volume=21&rft.issue=8&rft.spage=3411-3419&rft.epage=3411-3419&rft.eissn=1526-4602&rft.issn=1526-4602&rft.au=WANG,%20Zhiwei&LIN,%20Min&BONDUELLE,%20Colin&LI,%20Rongye&SHI,%20Zhekun&rft.genre=article |
