Self-assembled nanostructures from peptide-synthetic hybrid block copolymers: Complex, stimuli-responsive rod-coil architectures
LECOMMANDOUX, Sebastien
Laboratoire de Chimie des polymères organiques [LCPO]
Team 3 LCPO : Polymer Self-Assembly & Life Sciences
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Laboratoire de Chimie des polymères organiques [LCPO]
Team 3 LCPO : Polymer Self-Assembly & Life Sciences
LECOMMANDOUX, Sebastien
Laboratoire de Chimie des polymères organiques [LCPO]
Team 3 LCPO : Polymer Self-Assembly & Life Sciences
< Reduce
Laboratoire de Chimie des polymères organiques [LCPO]
Team 3 LCPO : Polymer Self-Assembly & Life Sciences
Language
en
Article de revue
This item was published in
Faraday Discussions. 2005, vol. 128, p. 179-192
Royal Society of Chemistry
English Abstract
The synthesis, solution and solid state self-assembly properties of a series of polyisoprene-b-poly(epsilon-benzyloxycarbonyl-L-lysine) PI-b-PZLys and polyisoprene-b-poly(L-lysine) PI-b-PLys block copolymers have been ...Read more >
The synthesis, solution and solid state self-assembly properties of a series of polyisoprene-b-poly(epsilon-benzyloxycarbonyl-L-lysine) PI-b-PZLys and polyisoprene-b-poly(L-lysine) PI-b-PLys block copolymers have been examined. The formation of stimuli-responsive micelles in water has been studied as a function of pH and ionic strength using static and dynamic light scattering, UV-circular dichroism and transmission electron microscopy. The observed change in the micelles dimensions has been directly attributed to the conformational transition in the secondary structure of polypeptide chains. In bulk, these rod-coil copolymers form self-assembled structures that have been characterized using DSC, DMA, WAXS and SAXS techniques. Hexagonal in lamellar (HL) and more interestingly hexagonal in hexagonal (HH) morphologies have been evidenced as a function of the chemical composition.Read less <
English Keywords
SCATTERING
EQUILIBRIUM
PHASE-BEHAVIOR
L-LYSINE
MORPHOLOGY
MICROPHASE SEPARATION
SUPRAMOLECULAR MATERIALS
DIBLOCK COPOLYMERS
POLYPEPTIDE BLOCK
TRANSITION
Origin
Hal imported