SEGOBIN, Shailendra; HAAST, Roy A. M.; KUMAR, Vinod Jangir; LELLA, Annalisa; ALKEMADE, Anneke; BACH CUADRA, Meritxell; BARBEAU, Emmanuel J.; FELICIAN, Olivier; PERGOLA, Giulio; PITEL, Anne-Lise; SARANATHAN, Manojkumar; TOURDIAS, Thomas; HORNBERGER, Michael

doi:10.1038/s41583-024-00867-1

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Nature Reviews Neuroscience. 2024-12, vol. 25, n° 12, p. 792 – 808

Résumé en anglais

The thalamus has a key role in mediating cortical–subcortical interactions but is often neglected in neuroimaging studies, which mostly focus on changes in cortical structure and activity. One of the main reasons for the thalamus being overlooked is that the delineation of individual thalamic nuclei via neuroimaging remains controversial. Indeed, neuroimaging atlases vary substantially regarding which thalamic nuclei are included and how their delineations were established. Here, we review current and emerging methods for thalamic nuclei segmentation in neuroimaging data and consider the limitations of existing techniques in terms of their research and clinical applicability. We address these challenges by proposing a roadmap to improve thalamic nuclei segmentation in human neuroimaging and, in turn, harmonize research approaches and advance clinical applications. We believe that a collective effort is required to achieve this. We hope that this will ultimately lead to the thalamic nuclei being regarded as key brain regions in their own right and not (as often currently assumed) as simply a gateway between cortical and subcortical regions. © Springer Nature Limited 2024.< Réduire

Mots clés en anglais

Humans

Neuroimaging

Human

Complication

Procedures

Article

Diagnostic Imaging

Etiology

Brain Mapping

Thalamus

Brain Region

Thalamic Nuclei

Thalamus Nucleus

Special Situation For Pharmacovigilance

URI

https://oskar-bordeaux.fr/handle/20.500.12278/206798

DOI

http://dx.doi.org/10.1038/s41583-024-00867-1

Unités de recherche

Neurocentre Magendie - U1215

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A roadmap towards standardized neuroimaging approaches for human thalamic nuclei

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Résumé en anglais

Mots clés en anglais

URI

DOI

Unités de recherche