Occupational exposure to ultrafine particles and lung cancer in a population exposed to asbestos
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Article de revue
Este ítem está publicado en
BMC Public Health. 2025-02-26, vol. 25, n° 1, p. 784
Resumen en inglés
BackgroundUltrafine particles are present in ever greater quantities in the workplace and only one epidemiological study to date has found an association with the occurrence of lung cancer.ObjectiveTo investigate the effect ...Leer más >
BackgroundUltrafine particles are present in ever greater quantities in the workplace and only one epidemiological study to date has found an association with the occurrence of lung cancer.ObjectiveTo investigate the effect of occupational exposure to ultrafine particles on the risk of lung cancer.MethodsThe ARDCO is a surveillance program involving retiree workers who had been exposed to asbestos during their working life. Exposure to ultrafine particles over the complete lifetime occupational history was assessed using the French job exposure matrix MATPUF. Cox proportional hazard models were used to estimate hazard ratios (HRs) and 95% confidence intervals (95% CI).ResultsThere was no association between exposure to ultrafine particles and lung cancer after adjustment for smoking and exposure to asbestos and crystalline silica.ConclusionThe findings do not indicate increased risks of lung cancer for UFP after adjustment for level of exposure to asbestos, crystalline silica, and smoking status.Clinical trial numberNot applicable.< Leer menos
Palabras clave en inglés
Asbestos
Lung cancer
Occupational exposures
Ultrafine particles
Centros de investigación