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Comparative in vitro cytotoxicity towards human osteoprogenitor cells of polycaprolactones synthesized from various metallic initiators
| dc.rights.license | open | |
| hal.structure.identifier | Laboratoire de Chimie des polymères organiques [LCPO] | |
| dc.contributor.author | SCHAPPACHER, M. | |
| hal.structure.identifier | Laboratoire de Chimie des polymères organiques [LCPO] | |
| dc.contributor.author | LE HELLAYE, M. | |
| hal.structure.identifier | Biomateriaux et Reparation Tissulaire | |
| dc.contributor.author | BAREILLE, R. | |
| hal.structure.identifier | Biomateriaux et Reparation Tissulaire | |
| dc.contributor.author | DURRIEU, M.-C. | |
| hal.structure.identifier | Organométalliques: Matériaux et Catalyse | |
| dc.contributor.author | GUILLAUME, Sophie | |
| dc.date.accessioned | 2020 | |
| dc.date.available | 2020 | |
| dc.date.issued | 2010 | |
| dc.identifier.issn | 1616-5187 | |
| dc.identifier.uri | https://oskar-bordeaux.fr/handle/20.500.12278/20598 | |
| dc.description.abstractEn | Various poly(ε-caprolactone)s (PCLs) prepared by ring-opening polymerization of ε-caprolactone (CL) initiated by a range of metallic derivatives such as alkoxides, Al(OiPr)3, La(OiPr)3, Sn(octanoate)2, Ti(OiPr)4, Zn[O(CH2)3NHtBoc]2, or borohydride La(BH4)3(THF)3 were evaluated for their in vitro cytotoxicity. The amount of residual metal present in the polymer samples was measured and compared to the initial quantity introduced. The effect of the metallic system on the biocompatibility profiles of the resulting polyesters was evaluated in vitro on PCL films from a series of cytotoxicity tests involving MTT and neutral red assays upon exposure to human osteoprogenitor cells. The absence of toxic influence of all these PCLs suggests that they may be used as biomaterials in contact with living human cells. | |
| dc.language.iso | en | |
| dc.publisher | Wiley-VCH Verlag | |
| dc.subject.en | cell metabolic activity (MTT) | |
| dc.subject.en | cell viability (NR) | |
| dc.subject.en | indirect cytotoxicity | |
| dc.subject.en | metallic initiator | |
| dc.subject.en | poly(ε-caprolactone) | |
| dc.subject.en | polyester | |
| dc.title.en | Comparative in vitro cytotoxicity towards human osteoprogenitor cells of polycaprolactones synthesized from various metallic initiators | |
| dc.type | Article de revue | |
| dc.identifier.doi | 10.1002/mabi.200900184 | |
| dc.subject.hal | Chimie/Catalyse | |
| bordeaux.journal | Macromolecular Bioscience | |
| bordeaux.page | 60-67 | |
| bordeaux.volume | 10 | |
| bordeaux.hal.laboratories | Laboratoire de Chimie des Polymères Organiques (LCPO) - UMR 5629 | * |
| bordeaux.issue | 1 | |
| bordeaux.institution | Bordeaux INP | |
| bordeaux.institution | Université de Bordeaux | |
| bordeaux.peerReviewed | oui | |
| hal.identifier | hal-00448819 | |
| hal.version | 1 | |
| hal.origin.link | https://hal.archives-ouvertes.fr//hal-00448819v1 | |
| bordeaux.COinS | ctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=Macromolecular%20Bioscience&rft.date=2010&rft.volume=10&rft.issue=1&rft.spage=60-67&rft.epage=60-67&rft.eissn=1616-5187&rft.issn=1616-5187&rft.au=SCHAPPACHER,%20M.&LE%20HELLAYE,%20M.&BAREILLE,%20R.&DURRIEU,%20M.-C.&GUILLAUME,%20Sophie&rft.genre=article |
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