Biologically Active Polymersomes from Amphiphilic Glycopeptides
| dc.rights.license | open | |
| hal.structure.identifier | Sch Chem Sci [Dublin City Univ] | |
| dc.contributor.author | HUANG, Jin | |
| hal.structure.identifier | Laboratoire de Chimie des Polymères Organiques [LCPO] | |
| dc.contributor.author | BONDUELLE, Colin
IDREF: 134527046 | |
| hal.structure.identifier | Laboratoire de Chimie des Polymères Organiques [LCPO] | |
| dc.contributor.author | THEVENOT, Julie | |
| hal.structure.identifier | Laboratoire de Chimie des Polymères Organiques [LCPO] | |
| hal.structure.identifier | Team 3 LCPO : Polymer Self-Assembly & Life Sciences | |
| dc.contributor.author | LECOMMANDOUX, Sebastien | |
| hal.structure.identifier | Sch Chem Sci [Dublin City Univ] | |
| dc.contributor.author | HEISE, Andreas | |
| dc.date.accessioned | 2020 | |
| dc.date.available | 2020 | |
| dc.date.issued | 2012 | |
| dc.identifier.issn | 0002-7863 | |
| dc.identifier.uri | https://oskar-bordeaux.fr/handle/20.500.12278/20472 | |
| dc.description.abstractEn | Polypeptide block copolymers with different block length ratios were obtained by sequential ring-opening polymerization of benzyl-L-glutamate and propargylglycine (PG) N-carboxyanhydrides. Glycosylation of the poly(PG) block was obtained by Huisgens cycloaddition "click" reaction using azide-functionalized galactose. All copolymers were self-assembled using the nanoprecipitation method to obtain spherical and wormlike micelles as well as polymersomes depending on the block length ratio and the nanoprecipitation conditions. These structures display bioactive galactose units in the polymersome shell, as proven by selective lectin binding experiments. | |
| dc.language.iso | en | |
| dc.publisher | American Chemical Society | |
| dc.subject.en | DRUG-DELIVERY | |
| dc.subject.en | RECOGNITION PROPERTIES | |
| dc.subject.en | MULTIPLE MORPHOLOGIES | |
| dc.subject.en | COPOLYMER VESICLES | |
| dc.subject.en | BLOCK-COPOLYMERS | |
| dc.subject.en | GENE DELIVERY | |
| dc.subject.en | BINDING | |
| dc.subject.en | GLYCOPROTEIN | |
| dc.subject.en | THERAPEUTICS | |
| dc.subject.en | LACTOSE | |
| dc.title.en | Biologically Active Polymersomes from Amphiphilic Glycopeptides | |
| dc.type | Article de revue | |
| dc.identifier.doi | 10.1021/ja209676p | |
| dc.subject.hal | Chimie/Polymères | |
| bordeaux.journal | Journal of the American Chemical Society | |
| bordeaux.page | 119-122 | |
| bordeaux.volume | 134 | |
| bordeaux.hal.laboratories | Laboratoire de Chimie des Polymères Organiques (LCPO) - UMR 5629 | * |
| bordeaux.issue | 1 | |
| bordeaux.institution | Bordeaux INP | |
| bordeaux.institution | Université de Bordeaux | |
| bordeaux.peerReviewed | oui | |
| hal.identifier | hal-00757517 | |
| hal.version | 1 | |
| hal.origin.link | https://hal.archives-ouvertes.fr//hal-00757517v1 | |
| bordeaux.COinS | ctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=Journal%20of%20the%20American%20Chemical%20Society&rft.date=2012&rft.volume=134&rft.issue=1&rft.spage=119-122&rft.epage=119-122&rft.eissn=0002-7863&rft.issn=0002-7863&rft.au=HUANG,%20Jin&BONDUELLE,%20Colin&THEVENOT,%20Julie&LECOMMANDOUX,%20Sebastien&HEISE,%20Andreas&rft.genre=article |
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