Disk-shaped compact tension test for fracture analysis on pharmaceutical tablets
Language
EN
Article de revue
This item was published in
Powder Technology. 2023-01-01, vol. 413, p. 118016
English Abstract
Pharmaceutical tablets must meet a number of requirements and among them, the mechanical strength plays an important role. The diametral compression test is generally used to evaluate it but can generate unstable failures. ...Read more >
Pharmaceutical tablets must meet a number of requirements and among them, the mechanical strength plays an important role. The diametral compression test is generally used to evaluate it but can generate unstable failures. Thanks to load–unload cycles applied to the tablets subjected to a DCT test, it was shown that the concept of equivalent linear elastic fracture mechanics usually, can be successfully applied to the Mode I fracture behavior. Within this framework, the equivalent elastic crack growth resistance, commonly called resistance curve (R-curve), of the studied material was obtained and revealed the development of a Fracture Process Zone (FPZ) which is symptomatic of a quasi-brittle behavior. Moreover, the cyclic loading applied during the fracture test revealed the existence of a second dissipative mechanism leading to residual crack opening which seems to be mainly caused by friction phenomenon in the FPZ.Read less <
English Keywords
DCT
Pharmaceutical tablet
Quasi-brittle fracture
Energy release rate
Fracture process zone
L.E.F.M. equivalent
R-curve
ANR Project
Clivage en compression pharmaceutique - ANR-17-CE08-0015