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dc.rights.licenseopen
hal.structure.identifierInstitut Européen de Chimie et de Biologie [IECB]
hal.structure.identifierLaboratoire de Chimie des Polymères Organiques [LCPO]
dc.contributor.authorDRAPPIER, Charlotte
hal.structure.identifierLaboratoire de Chimie des Polymères Organiques [LCPO]
dc.contributor.authorWIROTIUS, Anne-Laure
hal.structure.identifierChimie et Biologie des Membranes et des Nanoobjets [CBMN]
dc.contributor.authorBATHANY, Katell
hal.structure.identifierLaboratoire de Chimie des Polymères Organiques [LCPO]
dc.contributor.authorIBARBOURE, Emmanuel
hal.structure.identifierLaboratoire de Chimie des Polymères Organiques [LCPO]
dc.contributor.authorCONDASSAMY, Olivia
hal.structure.identifierInstitut Européen de Chimie et de Biologie [IECB]
hal.structure.identifierLaboratoire de Chimie des Polymères Organiques [LCPO]
hal.structure.identifierTeam 3 LCPO : Polymer Self-Assembly & Life Sciences
dc.contributor.authorGARANGER, Elisabeth
IDREF: 089451740
hal.structure.identifierLaboratoire de Chimie des Polymères Organiques [LCPO]
hal.structure.identifierTeam 3 LCPO : Polymer Self-Assembly & Life Sciences
dc.contributor.authorLECOMMANDOUX, Sebastien
dc.date.accessioned2020
dc.date.available2020
dc.date.issued2013
dc.identifier.issn1759-9954
dc.identifier.urihttps://oskar-bordeaux.fr/handle/20.500.12278/20411
dc.description.abstractEnWe describe the precision synthesis and characterization of amphiphilic peptide-b-polymer chimeras encoding, at the molecular level, self-assembly properties and biological functions, presently cell membrane penetrating motifs (Tat peptide). Self-assembled micellar nanoparticles obtained from a series of Tat-b-poly(trimethylene carbonate) (Tat-b-PTMC) chimeras with tunable hydrophilic fractions were finely characterized in order to establish chimera-nanoparticle structure relationships. Well-defined nanoparticles with diameters ranging from 22 to 40 nm could be obtained by direct self-assembly in buffer.
dc.language.isoen
dc.publisherRoyal Society of Chemistry - RSC
dc.subject.enHIV-1
dc.subject.enSIRNA
dc.subject.enMEMBRANE
dc.subject.enPROTEIN
dc.subject.enINTRACELLULAR DRUG-DELIVERY
dc.subject.enCELL-PENETRATING PEPTIDES
dc.subject.enSYNTHETIC-POLYMER
dc.subject.enBLOCK-COPOLYMERS
dc.subject.enTAT PEPTIDE
dc.subject.enSPECTROSCOPY
dc.title.enBiofunctional micellar nanoparticles from peptide-b-polymer chimeras
dc.typeArticle de revue
dc.identifier.doi10.1039/c2py21044d
dc.subject.halChimie/Polymères
bordeaux.journalPolymer Chemistry
bordeaux.page2011-2018
bordeaux.volume4
bordeaux.hal.laboratoriesLaboratoire de Chimie des Polymères Organiques (LCPO) - UMR 5629*
bordeaux.issue6
bordeaux.institutionBordeaux INP
bordeaux.institutionUniversité de Bordeaux
bordeaux.peerReviewedoui
hal.identifierhal-00846289
hal.version1
hal.origin.linkhttps://hal.archives-ouvertes.fr//hal-00846289v1
bordeaux.COinSctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=Polymer%20Chemistry&rft.date=2013&rft.volume=4&rft.issue=6&rft.spage=2011-2018&rft.epage=2011-2018&rft.eissn=1759-9954&rft.issn=1759-9954&rft.au=DRAPPIER,%20Charlotte&WIROTIUS,%20Anne-Laure&BATHANY,%20Katell&IBARBOURE,%20Emmanuel&CONDASSAMY,%20Olivia&rft.genre=article


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