Synthesis and Antibacterial Activity of Aminodeoxyglucose Derivatives against Listeria innocua and Salmonella typhimurium
| dc.rights.license | open | |
| hal.structure.identifier | Unité des Sciences du bois et des biopolymères [Us2b] | |
| dc.contributor.author | MUHIZI, Theoneste | |
| hal.structure.identifier | Laboratoire de Chimie des Polymères Organiques [LCPO] | |
| hal.structure.identifier | Team 2 LCPO : Biopolymers & Bio-sourced Polymers | |
| dc.contributor.author | GRELIER, Stéphane | |
| hal.structure.identifier | Laboratoire de Chimie des Polymères Organiques [LCPO] | |
| hal.structure.identifier | Team 2 LCPO : Biopolymers & Bio-sourced Polymers | |
| dc.contributor.author | COMA, Veronique | |
| dc.date.accessioned | 2020 | |
| dc.date.available | 2020 | |
| dc.date.issued | 2009 | |
| dc.identifier.issn | 0021-8561 | |
| dc.identifier.uri | https://oskar-bordeaux.fr/handle/20.500.12278/20384 | |
| dc.description.abstractEn | In this study aminodeoxyglucose derivatives were synthesized and evaluated for their antibacterial activity against two food bacteria, Listeria innocua and Salmonella typhimurium. 6-Amino-6-deoxy-alpha-D-methylglucopyranose (GSA-6), 3-amino-3-deoxy-D-glucopyranoside (GSA-3), and beta-D-glucopyranosylamine (GSA-1) were synthesized and concurrently tested with commercially available D-glucosamine (GSA-2) for antibacterial activity. Results obtained from this study showed a pronounced antagonist effect due to the position of amino groups of aminoglucose derivatives on the antibacterial activity. GSA-3 was the most active compound. At a concentration of 2 x 10(-4) mol mL(-1), it delayed the growth of both bacteria with percentages of inhibition of 29 and 15% for L. innocua and S. typhimurium, respectively. At the same concentration the percentages of inhibition for other aminodeoxyglucoses varied between 5 and 18% and between 2 and 11% for L. innocua and S. typhimurium, respectively. All compounds were characterized by FTIR, (1)H NMR, and (13)C NMR spectroscopy. | |
| dc.language.iso | en | |
| dc.publisher | American Chemical Society | |
| dc.subject.en | Antibacterial activity | |
| dc.subject.en | aminodeoxyglucoses | |
| dc.subject.en | Salmonella typhimurium | |
| dc.subject.en | Listeria innocua | |
| dc.title.en | Synthesis and Antibacterial Activity of Aminodeoxyglucose Derivatives against Listeria innocua and Salmonella typhimurium | |
| dc.type | Article de revue | |
| dc.identifier.doi | 10.1021/jf901609y | |
| dc.subject.hal | Chimie/Polymères | |
| bordeaux.journal | Journal of Agricultural and Food Chemistry | |
| bordeaux.page | 8770-8775 | |
| bordeaux.volume | 57 | |
| bordeaux.hal.laboratories | Laboratoire de Chimie des Polymères Organiques (LCPO) - UMR 5629 | * |
| bordeaux.issue | 19 | |
| bordeaux.institution | Bordeaux INP | |
| bordeaux.institution | Université de Bordeaux | |
| bordeaux.peerReviewed | oui | |
| hal.identifier | hal-00944893 | |
| hal.version | 1 | |
| hal.origin.link | https://hal.archives-ouvertes.fr//hal-00944893v1 | |
| bordeaux.COinS | ctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=Journal%20of%20Agricultural%20and%20Food%20Chemistry&rft.date=2009&rft.volume=57&rft.issue=19&rft.spage=8770-8775&rft.epage=8770-8775&rft.eissn=0021-8561&rft.issn=0021-8561&rft.au=MUHIZI,%20Theoneste&GRELIER,%20St%C3%A9phane&COMA,%20Veronique&rft.genre=article |
Fichier(s) constituant ce document
| Fichiers | Taille | Format | Vue |
|---|---|---|---|
|
Il n'y a pas de fichiers associés à ce document. |
|||