pH and redox responsive hydrogels and nanogels made from poly(2-ethyl-2-oxazoline)
| dc.rights.license | open | |
| hal.structure.identifier | Laboratory of Mammalian Cell Culture [GIGA-R] | |
| hal.structure.identifier | Laboratoire de Chimie des Polymères Organiques [LCPO] | |
| dc.contributor.author | LEGROS, Camille | |
| hal.structure.identifier | Laboratory of Mammalian Cell Culture [GIGA-R] | |
| dc.contributor.author | DE PAUW-GILLET, Marie-Claire | |
| hal.structure.identifier | University of Waterloo [Waterloo] | |
| dc.contributor.author | TAM, Kam Chiu | |
| hal.structure.identifier | Laboratoire de Chimie des Polymères Organiques [LCPO] | |
| hal.structure.identifier | Team 3 LCPO : Polymer Self-Assembly & Life Sciences | |
| dc.contributor.author | LECOMMANDOUX, Sebastien | |
| hal.structure.identifier | Laboratoire de Chimie des Polymères Organiques [LCPO] | |
| hal.structure.identifier | Team 1 LCPO : Polymerization Catalyses & Engineering | |
| dc.contributor.author | TATON, Daniel | |
| dc.date.accessioned | 2020 | |
| dc.date.available | 2020 | |
| dc.date.issued | 2013 | |
| dc.identifier.issn | 1759-9954 | |
| dc.identifier.uri | https://oskar-bordeaux.fr/handle/20.500.12278/20332 | |
| dc.description.abstractEn | Hydrogels and nanogels made from partially hydrolyzed poly(2-ethyl-2-oxazoline) (PEtOx) were prepared by two different processes. First, both hydrogels and nanogels were made in dilute media in the presence of 1,6-hexanediol di-glycidyl ether (1) as the cross-linker. Alternatively, the PEtOx precursor was engineered into nanogels by an inverse w/o emulsion process. In the latter case, in addition to cross-linker 1,a cleavable cross-linker homologue (2), namely 1,6-hydroxyethyl disulfide-bis-di-glycidyl ether, was used to produce cleavable nanogels. The pH-responsiveness of all cross-linked PEtOx derivatives was demonstrated in an acidic environment, owing to the protonation of residual ethylene imine groups and/or tertiary amines formed during the cross-linking reaction. Nanogels derived from cross-linker 2 could readily be cleaved under a reducing environment, due to the presence of disulfide linkages at the cross-linking points. | |
| dc.language.iso | en | |
| dc.publisher | Royal Society of Chemistry - RSC | |
| dc.subject.en | POLYMER | |
| dc.subject.en | POLYOXAZOLINES | |
| dc.subject.en | 2-METHYL-2-OXAZOLINE | |
| dc.subject.en | BLOCK-COPOLYMER MICELLES | |
| dc.subject.en | BIOMEDICAL APPLICATIONS | |
| dc.subject.en | NONIONIC HYDROGEL | |
| dc.subject.en | DRUG-DELIVERY | |
| dc.subject.en | POLY(ETHYLENE GLYCOL) | |
| dc.subject.en | SENSITIVE HYDROGELS | |
| dc.subject.en | POLY(2-OXAZOLINE)S | |
| dc.title.en | pH and redox responsive hydrogels and nanogels made from poly(2-ethyl-2-oxazoline) | |
| dc.type | Article de revue | |
| dc.identifier.doi | 10.1039/c3py00685a | |
| dc.subject.hal | Chimie/Polymères | |
| bordeaux.journal | Polymer Chemistry | |
| bordeaux.page | 4801-4808 | |
| bordeaux.volume | 4 | |
| bordeaux.hal.laboratories | Laboratoire de Chimie des Polymères Organiques (LCPO) - UMR 5629 | * |
| bordeaux.issue | 17 | |
| bordeaux.institution | Bordeaux INP | |
| bordeaux.institution | Université de Bordeaux | |
| bordeaux.peerReviewed | oui | |
| hal.identifier | hal-00959609 | |
| hal.version | 1 | |
| hal.origin.link | https://hal.archives-ouvertes.fr//hal-00959609v1 | |
| bordeaux.COinS | ctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=Polymer%20Chemistry&rft.date=2013&rft.volume=4&rft.issue=17&rft.spage=4801-4808&rft.epage=4801-4808&rft.eissn=1759-9954&rft.issn=1759-9954&rft.au=LEGROS,%20Camille&DE%20PAUW-GILLET,%20Marie-Claire&TAM,%20Kam%20Chiu&LECOMMANDOUX,%20Sebastien&TATON,%20Daniel&rft.genre=article |
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