Iminosugar-based glycopolypeptides: glycosidase inhibition with bioinspired glycoprotein analogue micellar self-assemblies
LECOMMANDOUX, Sebastien
Laboratoire de Chimie des Polymères Organiques [LCPO]
Team 3 LCPO : Polymer Self-Assembly & Life Sciences
< Reduce
Laboratoire de Chimie des Polymères Organiques [LCPO]
Team 3 LCPO : Polymer Self-Assembly & Life Sciences
Language
en
Article de revue
This item was published in
Chemical Communications. 2014, vol. 50, n° 25, p. 3350-3352
Royal Society of Chemistry
English Abstract
Biomimetic nanoparticles prepared by self-assembly of iminosugar-based glycopolypeptides evidenced remarkablemultivalency properties when inhibiting alpha-mannosidase activity. This approach paves the way to obtain ...Read more >
Biomimetic nanoparticles prepared by self-assembly of iminosugar-based glycopolypeptides evidenced remarkablemultivalency properties when inhibiting alpha-mannosidase activity. This approach paves the way to obtain biologically active drug delivery systems having glycosidase inhibition potency.Read less <
English Keywords
POLYPEPTIDES
LECTINS
BINDING
CLICK CLUSTERS
MULTIVALENT
FUNCTIONALIZATION
GLYCOPOLYMERS
GLYCOPEPTIDES
GLYCOBIOLOGY
RING-OPENING POLYMERIZATION
Origin
Hal imported