Remodeling of the cycling transcriptome of the oyster Crassostrea gigas by the harmful algae Alexandrium minutum
HOEDE, Claire
Unité de Mathématiques et Informatique Appliquées de Toulouse [MIAT INRA]
Plateforme Bio-Informatique - Génotoul
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Unité de Mathématiques et Informatique Appliquées de Toulouse [MIAT INRA]
Plateforme Bio-Informatique - Génotoul
HOEDE, Claire
Unité de Mathématiques et Informatique Appliquées de Toulouse [MIAT INRA]
Plateforme Bio-Informatique - Génotoul
< Reduce
Unité de Mathématiques et Informatique Appliquées de Toulouse [MIAT INRA]
Plateforme Bio-Informatique - Génotoul
Language
EN
Article de revue
This item was published in
Scientific Reports. 2017-06-14, vol. 7, p. np
English Abstract
As a marine organism, the oyster Crassostrea gigas inhabits a complex biotope governed by interactions between the moon and the sun cycles. We used next-generation sequencing to investigate temporal regulation of oysters ...Read more >
As a marine organism, the oyster Crassostrea gigas inhabits a complex biotope governed by interactions between the moon and the sun cycles. We used next-generation sequencing to investigate temporal regulation of oysters under light/dark entrainment and the impact of harmful algal exposure. We found that approximate to 6% of the gills' transcriptome exhibits circadian expression, characterized by a nocturnal and bimodal pattern. Surprisingly, a higher number of ultradian transcripts were also detected under solely circadian entrainment. The results showed that a bloom of Alexandrium minutum generated a remodeling of the bivalve's temporal structure, characterized by a loss of oscillations, a genesis of de novo oscillating transcripts, and a switch in the period of oscillations. These findings provide unprecedented insights into the diurnal landscape of the oyster's transcriptome and pleiotropic remodeling due to toxic algae exposure, revealing the intrinsic plasticity of the cycling transcriptome in oysters.Read less <
English Keywords
MAMMALIAN CIRCADIAN CLOCK
DIFFERENTIAL EXPRESSION ANALYSIS
PARALYTIC SHELLFISH TOXINS
GENE-EXPRESSION
SUPRACHIASMATIC NUCLEUS
FEEDING RESPONSES
MOUSE-LIVER
SHIFT WORK
DINOFLAGELLATE
RHYTHMS