FAN, Bo; TRANT, John Frederick; HEMERY, Gauvin; SANDRE, Olivier; GILLIES, Elizabeth R.

doi:10.1039/C7CC06410A

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FAN, Bo

TRANT, John Frederick

HEMERY, Gauvin
Laboratoire de Chimie des Polymères Organiques [LCPO]
Team 3 LCPO : Polymer Self-Assembly & Life Sciences

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Chemical Communications. 2017, vol. 53, n° 89, p. 12068-12071

Royal Society of Chemistry

Resumen en inglés

A thermo-responsive end-cap based on a retro-Diels-Alder and subsequent furan elimination reaction was developed. It was used to cap poly(ethyl glyoxylate), allowing end-to-end depolymerization upon thermal triggering. Using a multifunctional derivative for the preparation of block copolymers, thermo-responsive micelles and vesicles were prepared and shown to disassemble upon heating. Thermal degradation could also be triggered indirectly by magnetic field hyperthermia after incorporation of iron oxide nanoparticles into the assemblies.< Leer menos

URI

https://oskar-bordeaux.fr/handle/20.500.12278/19978

DOI

http://dx.doi.org/10.1039/C7CC06410A

Proyecto ANR

Magnéto-Chimiothérapie : Modélisation de la Délivrance Induite par Champ Magnétique Radiofréquence d'Anticancéreux par des Nano-Vésicules Polymères et Suivi par IRM d'un Modèle de Glioblastome - ANR-13-BS08-0017

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Centros de investigación

Laboratoire de Chimie des Polymères Organiques (LCPO) - UMR 5629