ZHUKOVA, Anna; SHERMAN, David James

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ZHUKOVA, Anna
Models and Algorithms for the Genome [MAGNOME]
Laboratoire Bordelais de Recherche en Informatique [LaBRI]

SHERMAN, David James
Models and Algorithms for the Genome [MAGNOME]

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Autre communication scientifique (congrès sans actes - poster - séminaire...)

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Journées EDMI, 2014-11-04, Bordeaux.

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The complexity of genome-scale metabolic models makes them quite difficult for human users to read, since they contain thousands of reactions that must be included for accurate computer simulation. The web-based navigation system Mimoza allows a human expert to explore metabolic network models in a semantically zoomable manner: The most general view represents the compartments of the model; the next view shows the generalized versions of reactions and metabolites in each compartment; and the most detailed view represents the initial network with the generalization-based layout (where similar metabolites and reactions are placed next to each other). It allows a human expert to grasp the general structure of the network and analyze it in a top-down manner.< Leer menos

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Metabolic modeling

model generalization

visualization

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Three-level representation of metabolic networks

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