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QTL dissection of Lag phase in wine fermentation reveals a new translocation responsible for Saccharomyces cerevisiae adaptation to sulfite.

hal.structure.identifierLaffort [Floirac]
dc.contributor.authorZIMMER, Adrien
hal.structure.identifierInstitut de Veille Sanitaire [INVS]
hal.structure.identifierLaffort [Floirac]
dc.contributor.authorDURAND, Cécile
hal.structure.identifierLaboratoire Bordelais de Recherche en Informatique [LaBRI]
hal.structure.identifierModels and Algorithms for the Genome [ MAGNOME]
dc.contributor.authorLOIRA, Nicolás
hal.structure.identifierLaboratoire Bordelais de Recherche en Informatique [LaBRI]
hal.structure.identifierModels and Algorithms for the Genome [ MAGNOME]
dc.contributor.authorDURRENS, Pascal
hal.structure.identifierLaboratoire Bordelais de Recherche en Informatique [LaBRI]
hal.structure.identifierModels and Algorithms for the Genome [ MAGNOME]
dc.contributor.authorSHERMAN, David James
hal.structure.identifierFaculté d'Oenologie [Bordeaux II]
hal.structure.identifierLaffort [Floirac]
dc.contributor.authorMARULLO, Philippe
dc.date.accessioned2024-04-15T09:55:51Z
dc.date.available2024-04-15T09:55:51Z
dc.date.issued2014
dc.identifier.issn1932-6203
dc.identifier.urihttps://oskar-bordeaux.fr/handle/20.500.12278/198781
dc.description.abstractEnQuantitative genetics and QTL mapping are efficient strategies for deciphering the genetic polymorphisms that explain the phenotypic differences of individuals within the same species. Since a decade, this approach has been applied to eukaryotic microbes such as Saccharomyces cerevisiae in order to find natural genetic variations conferring adaptation of individuals to their environment. In this work, a QTL responsible for lag phase duration in the alcoholic fermentation of grape juice was dissected by reciprocal hemizygosity analysis. After invalidating the effect of some candidate genes, a chromosomal translocation affecting the lag phase was brought to light using de novo assembly of parental genomes. This newly described translocation (XV-t-XVI) involves the promoter region of ADH1 and the gene SSU1 and confers an increased expression of the sulfite pump during the first hours of alcoholic fermentation. This translocation constitutes another adaptation route of wine yeast to sulfites in addition to the translocation VIII-t-XVI previously described. A population survey of both translocation forms in a panel of domesticated yeast strains suggests that the translocation XV-t-XVI has been empirically selected by human activity.
dc.language.isoen
dc.publisherPublic Library of Science
dc.title.enQTL dissection of Lag phase in wine fermentation reveals a new translocation responsible for Saccharomyces cerevisiae adaptation to sulfite.
dc.typeArticle de revue
dc.identifier.doi10.1371/journal.pone.0086298
dc.subject.halInformatique [cs]/Bio-informatique [q-bio.QM]
dc.subject.halSciences du Vivant [q-bio]/Bio-Informatique, Biologie Systémique [q-bio.QM]
bordeaux.journalPLoS ONE
bordeaux.pagee86298
bordeaux.volume9
bordeaux.hal.laboratoriesLaboratoire Bordelais de Recherche en Informatique (LaBRI) - UMR 5800*
bordeaux.issue1
bordeaux.institutionUniversité de Bordeaux
bordeaux.institutionBordeaux INP
bordeaux.institutionCNRS
bordeaux.peerReviewedoui
hal.identifierhal-00986680
hal.version1
hal.popularnon
hal.audienceInternationale
dc.subject.itQTL
dc.subject.itgenome sequencing
dc.subject.itoenology
dc.subject.itquantitative genetics
hal.origin.linkhttps://hal.archives-ouvertes.fr//hal-00986680v1
bordeaux.COinSctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=PLoS%20ONE&rft.date=2014&rft.volume=9&rft.issue=1&rft.spage=e86298&rft.epage=e86298&rft.eissn=1932-6203&rft.issn=1932-6203&rft.au=ZIMMER,%20Adrien&DURAND,%20C%C3%A9cile&LOIRA,%20Nicol%C3%A1s&DURRENS,%20Pascal&SHERMAN,%20David%20James&rft.genre=article


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