Genome-wide identification of new Wnt/beta-catenin target genes in the human genome using CART method.
HÖDAR, Christian
Instituto de Nutricion y Tecnologia de los Alimentos [Santiago] [INTA]
Laboratorio de Bioinformática y Expresión Génica
Instituto de Nutricion y Tecnologia de los Alimentos [Santiago] [INTA]
Laboratorio de Bioinformática y Expresión Génica
ASSAR, Rodrigo
Models and Algorithms for the Genome [MAGNOME]
Departamento de Ingenieria Matematica, Centro Modelamiento Matematico
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Models and Algorithms for the Genome [MAGNOME]
Departamento de Ingenieria Matematica, Centro Modelamiento Matematico
HÖDAR, Christian
Instituto de Nutricion y Tecnologia de los Alimentos [Santiago] [INTA]
Laboratorio de Bioinformática y Expresión Génica
Instituto de Nutricion y Tecnologia de los Alimentos [Santiago] [INTA]
Laboratorio de Bioinformática y Expresión Génica
ASSAR, Rodrigo
Models and Algorithms for the Genome [MAGNOME]
Departamento de Ingenieria Matematica, Centro Modelamiento Matematico
Models and Algorithms for the Genome [MAGNOME]
Departamento de Ingenieria Matematica, Centro Modelamiento Matematico
PAVEZ, Leonardo
Laboratorio de Bioinformática y Expresión Génica
Instituto de Nutricion y Tecnologia de los Alimentos [Santiago] [INTA]
Departamento de Ingenieria Matematica, Centro Modelamiento Matematico
Laboratorio de Bioinformática y Expresión Génica
Instituto de Nutricion y Tecnologia de los Alimentos [Santiago] [INTA]
Departamento de Ingenieria Matematica, Centro Modelamiento Matematico
MAASS, Alejandro
Centre de modélisation mathématique / Centro de Modelamiento Matemático [Santiago] [CMM]
< Reduce
Centre de modélisation mathématique / Centro de Modelamiento Matemático [Santiago] [CMM]
Language
en
Article de revue
This item was published in
BMC Genomics. 2010, vol. 11, p. 348
BioMed Central
English Abstract
Our multiple CART strategy proved to be an effective tool to identify new Wnt/beta-catenin pathway targets based on the study of their regulatory regions in the human genome. In particular, several of these genes represent ...Read more >
Our multiple CART strategy proved to be an effective tool to identify new Wnt/beta-catenin pathway targets based on the study of their regulatory regions in the human genome. In particular, several of these genes represent a new group of transcriptional dependent targets of the canonical Wnt pathway. The functions of these genes indicate that they are involved in pathophysiology related to Alzheimer's disease or other brain disorders.Read less <
Origin
Hal imported