In various crop species, high levels of powdery mildew infection and severity have been associated with high vegetative vigour. In grapevine this relationship has also been observed by vine growers, though it has not been quantified. This study was undertaken to investigate the relationship between the development of powdery mildew on leaves and berries and canopy growth, and thus to quantify the relationship between the pathogen and its host. Over a two-year period (2005 and 2006), an experiment was carried out in a vineyard (cv. Aranel) near Montpellier, southern France. Several levels of canopy growth were generated by implementing four soil management strategies: i) perennial cover crop in the inter-row, ii) annual cover crop in the inter-row, iii) chemical weed control over the entire soil surface, iv) chemical weed control all over the soil surface and drip irrigation and fertilization in the row. Powdery mildew was artificially inoculated on experimental sub-plots with Erysiphe necator [Schw.] Burr. conidia. The most vigorous vines developed a larger number of diseased leaves and a higher percentage of mildewed berries compared to low-vigour vines. The major explanatory variable highlighted in these experiments was the shoot leaf number, mainly early in the season. A higher leaf population generated a larger number of powdery mildew colonies close to grapes and consequently a higher probability of berry infection. Our experimental results provide evidence of a positive relationship between powdery mildew development and grapevine vegetative development. These results provide an opportunity to develop new IPM strategies in vineyardsRead less <