Synthetic Polypeptide Polymers as Simplified Analogues of Antimicrobial Peptides
| dc.rights.license | open | |
| hal.structure.identifier | Laboratoire de Chimie des Polymères Organiques [LCPO] | |
| hal.structure.identifier | Team 3 LCPO : Polymer Self-Assembly & Life Sciences | |
| dc.contributor.author | SALAS-AMBROSIO, Pedro | |
| hal.structure.identifier | Laboratoire de chimie de coordination [LCC] | |
| dc.contributor.author | TRONNET, Antoine | |
| hal.structure.identifier | Laboratoire de chimie de coordination [LCC] | |
| dc.contributor.author | VERHAEGHE, Pierre | |
| hal.structure.identifier | Laboratoire de Chimie des Polymères Organiques [LCPO] | |
| hal.structure.identifier | Team 3 LCPO : Polymer Self-Assembly & Life Sciences | |
| dc.contributor.author | BONDUELLE, Colin
IDREF: 134527046 | |
| dc.date.accessioned | 2020 | |
| dc.date.available | 2020 | |
| dc.date.issued | 2020 | |
| dc.identifier.issn | 1525-7797 | |
| dc.identifier.uri | https://oskar-bordeaux.fr/handle/20.500.12278/19579 | |
| dc.description.abstractEn | Antimicrobial peptides (AMPs) are naturally occurring macromolecules made of amino acids that are potent broad-spectrum antibiotics with potential as novel therapeutic agents. This review aims to summarize the fundamental principles concerning the structure and mechanism of action of these AMPs, in order to guide the design of polymeric analogues that organic chemistry can generate. Among those simplified analogues, this review particularly focuses on those made of amino acids called polypeptide polymers: they are showing great potential by providing one of the best biomimetic and bioactive structures for further biomaterials science applications. | |
| dc.description.sponsorship | Analogues Polymériques de Peptides Antimicrobiens à Potentiel Thérapeutique anti-Clostridium difficile - ANR-17-CE07-0039 | |
| dc.language.iso | en | |
| dc.publisher | American Chemical Society | |
| dc.subject.en | anti-infective activity | |
| dc.subject.en | synthetic polymers | |
| dc.subject.en | polypeptides | |
| dc.subject.en | N-carboxyanhydride | |
| dc.subject.en | anti-infective agents | |
| dc.subject.en | amphiphilicity | |
| dc.subject.en | ring-opening polymerization | |
| dc.subject.en | amino-acid copolymers | |
| dc.subject.en | Antimicrobial peptides | |
| dc.title.en | Synthetic Polypeptide Polymers as Simplified Analogues of Antimicrobial Peptides | |
| dc.type | Article de revue | |
| dc.identifier.doi | 10.1021/acs.biomac.0c00797 | |
| dc.subject.hal | Chimie/Polymères | |
| dc.subject.hal | Chimie/Chimie organique | |
| bordeaux.journal | Biomacromolecules | |
| bordeaux.page | 10.1021/acs.biomac.0c00797 | |
| bordeaux.volume | 21 | |
| bordeaux.hal.laboratories | Laboratoire de Chimie des Polymères Organiques (LCPO) - UMR 5629 | * |
| bordeaux.issue | 9 | |
| bordeaux.institution | Bordeaux INP | |
| bordeaux.institution | Université de Bordeaux | |
| bordeaux.peerReviewed | oui | |
| hal.identifier | hal-02931945 | |
| hal.version | 1 | |
| hal.origin.link | https://hal.archives-ouvertes.fr//hal-02931945v1 | |
| bordeaux.COinS | ctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=Biomacromolecules&rft.date=2020&rft.volume=21&rft.issue=9&rft.spage=10.1021/acs.biomac.0c00797&rft.epage=10.1021/acs.biomac.0c00797&rft.eissn=1525-7797&rft.issn=1525-7797&rft.au=SALAS-AMBROSIO,%20Pedro&TRONNET,%20Antoine&VERHAEGHE,%20Pierre&BONDUELLE,%20Colin&rft.genre=article |
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