Theoretical connections between mathematical neuronal models corresponding to different expressions of noise
HENRY, Jacques
Modélisation et calculs pour l'électrophysiologie cardiaque [CARMEN]
Institut de Mathématiques de Bordeaux [IMB]
Modélisation et calculs pour l'électrophysiologie cardiaque [CARMEN]
Institut de Mathématiques de Bordeaux [IMB]
HENRY, Jacques
Modélisation et calculs pour l'électrophysiologie cardiaque [CARMEN]
Institut de Mathématiques de Bordeaux [IMB]
< Reduce
Modélisation et calculs pour l'électrophysiologie cardiaque [CARMEN]
Institut de Mathématiques de Bordeaux [IMB]
Language
en
Article de revue
This item was published in
Journal of Theoretical Biology. 2016, vol. 406, p. 31-41
Elsevier
English Abstract
Identifying the right tools to express the stochastic aspects of neural activity has proven to be one of the biggest challenges in computational neuroscience. Even if there is no definitive answer to this issue, the most ...Read more >
Identifying the right tools to express the stochastic aspects of neural activity has proven to be one of the biggest challenges in computational neuroscience. Even if there is no definitive answer to this issue, the most common procedure to express this randomness is the use of stochastic models. In accordance with the origin of variability, the sources of randomness are classified as intrinsic or extrinsic and give rise to distinct mathematical frameworks to track down the dynamics of the cell. While the external variability is generally treated by the use of a Wiener process in models such as the Integrate-and-Fire model, the internal variability is mostly expressed via a random firing process. In this paper, we investigate how those distinct expressions of variability can be related. To do so, we examine the probability density functions to the corresponding stochastic models and investigate in what way they can be mapped one to another via integral transforms. Our theoretical findings offer a new insight view into the particular categories of variability and it confirms that, despite their contrasting nature, the mathematical formalization of internal and external variability are strikingly similar.Read less <
English Keywords
Fokker-Planck equation
Age structured model
Neural noise
Noisy Leaky Integrate-and-Fire model
Escape rate
Origin
Hal imported