Impact of the endocardium in a parameter optimization to solve the inverse problem of electrocardiography
RAVON, Gwladys
IHU-LIRYC
Université de Bordeaux [UB]
Centre de recherche Cardio-Thoracique de Bordeaux [Bordeaux] [CRCTB]
IHU-LIRYC
Université de Bordeaux [UB]
Centre de recherche Cardio-Thoracique de Bordeaux [Bordeaux] [CRCTB]
COUDIÈRE, Yves
Modélisation et calculs pour l'électrophysiologie cardiaque [CARMEN]
IHU-LIRYC
Institut de Mathématiques de Bordeaux [IMB]
Modélisation et calculs pour l'électrophysiologie cardiaque [CARMEN]
IHU-LIRYC
Institut de Mathématiques de Bordeaux [IMB]
POTSE, Mark
IHU-LIRYC
Modélisation et calculs pour l'électrophysiologie cardiaque [CARMEN]
Institut de Mathématiques de Bordeaux [IMB]
See more >
IHU-LIRYC
Modélisation et calculs pour l'électrophysiologie cardiaque [CARMEN]
Institut de Mathématiques de Bordeaux [IMB]
RAVON, Gwladys
IHU-LIRYC
Université de Bordeaux [UB]
Centre de recherche Cardio-Thoracique de Bordeaux [Bordeaux] [CRCTB]
IHU-LIRYC
Université de Bordeaux [UB]
Centre de recherche Cardio-Thoracique de Bordeaux [Bordeaux] [CRCTB]
COUDIÈRE, Yves
Modélisation et calculs pour l'électrophysiologie cardiaque [CARMEN]
IHU-LIRYC
Institut de Mathématiques de Bordeaux [IMB]
Modélisation et calculs pour l'électrophysiologie cardiaque [CARMEN]
IHU-LIRYC
Institut de Mathématiques de Bordeaux [IMB]
POTSE, Mark
IHU-LIRYC
Modélisation et calculs pour l'électrophysiologie cardiaque [CARMEN]
Institut de Mathématiques de Bordeaux [IMB]
IHU-LIRYC
Modélisation et calculs pour l'électrophysiologie cardiaque [CARMEN]
Institut de Mathématiques de Bordeaux [IMB]
DUBOIS, Rémi
Centre de recherche Cardio-Thoracique de Bordeaux [Bordeaux] [CRCTB]
IHU-LIRYC
Université de Bordeaux [UB]
< Reduce
Centre de recherche Cardio-Thoracique de Bordeaux [Bordeaux] [CRCTB]
IHU-LIRYC
Université de Bordeaux [UB]
Language
en
Article de revue
This item was published in
Frontiers in Physiology. 2019, vol. 9, p. 1946
Frontiers
English Abstract
Electrocardiographic imaging aims at reconstructing cardiac electrical events from electrical signals measured on the body surface. The most common approach relies on the inverse solution of the Laplace equation in the ...Read more >
Electrocardiographic imaging aims at reconstructing cardiac electrical events from electrical signals measured on the body surface. The most common approach relies on the inverse solution of the Laplace equation in the torso to reconstruct epicardial potential maps from body surface potential maps. Here we apply a method based on a parameter identification problem to reconstruct both activation and repolarization times. From an ansatz of action potential, based on the Mitchell-Schaeffer ionic model, we compute body surface potential signals. The inverse problem is reduced to the identification of the parameters of the Mitchell-Schaeffer model. We investigate whether solving the inverse problem with the endocardium improves the results or not. We solved the parameter identification problem on two different meshes: one with only the epicardium, and one with both the epicardium and the endocardium. We compared the results on both the heart (activation and repolarization times) and the torso. The comparison was done on validation data of sinus rhythm and ventricular pacing. We found similar results with both meshes in 6 cases out of 7: the presence of the endocardium slightly improved the activation times. This was the most visible on a sinus beat, leading to the conclusion that inclusion of the endocardium would be useful in situations where endo-epicardial gradients in activation or repolarization times play an important role.Read less <
English Keywords
Parameter optimization
Endocardium
ECGI
Gradient descent method
Mitchell-Schaeffer
Endoepicardial gradients
ANR Project
L'Institut de Rythmologie et modélisation Cardiaque - ANR-10-IAHU-0004
Origin
Hal imported